DNM 26 DNM 26

Dutch
Neuroscience Meeting

Dutch
Neuroscience Meeting

Dutch
Neuroscience Meeting

Tiel, The Netherlands • 25-26 June 2026

Tiel, The Netherlands
25-26 June 2026

Tiel, The Netherlands
25-26 June 2026

Programme

Programme

Programme

  • Thursday, 25 June
  • Friday, 26 June
  • Poster presentations
  • 09:00 Registration (with Coffee & Tea)

    10:00 Opening

    10:10 Plenary Session
    Session 1: Keynote Lecture
    Chairs: Aleksandra Badura (Rotterdam) & Chun-Xia Yi (Amsterdam)

    Margaret McCarthy  (Baltimore, MD, USA) Power Play: How Steroids, Endocannabinoids and Behavior Sculpt Neural Development. (45')

    11:10 Coffee & Tea

    11:30 Parallel Sessions A
    Session 2: Illuminating endocannabinoid action in neural circuits[Tuin & Waterkers]
    Chairs: Daan van der Vliet (Rotterdam) & Tom van der Wel (Leiden)

    István Katona  (Bloomington, IN, USA) ImmunoSTORM and PharmacoSTORM super-resolution imaging of cannabinoid signaling in neurons and astrocytes (30')
    Jeroen Punt  (Leiden) Bioorthogonal probes to visualize endocannabinoids and their metabolism   (20')
    Corette Wierenga  (Nijmegen) Endocannabinoids as mediators of local coordination of excitatory and inhibitory synapses
      (20')

    Sylvie Lesuis  (Amsterdam) Stress-induced memory overgeneralization: The central role of endocannabinoid signaling (20')

    Session 3: Building and leveraging large-scale single-cell censuses for neuroscience[Pink Lady]
    Chairs: Vanessa Donega (Amsterdam) & Kimberly Siletti (Utrecht)

    Rebecca Hodge  (Seattle, WA, USA) Charting the cellular architecture of the human and non-human primate brain (30')
    Christiaan de Kock  (Amsterdam) Divergent Transcriptomic and Functional aging of Molecularly Defined Neuron Types in Human Brain (15')
    Eileen Brouwer  (Utrecht) Cellular underpinnings of eating disorders (15')
    Bart Eggen  (Groningen) The human CNS from a spatial perspective (15')
    Aletta van den Bosch  (Milan, Italy) Microglial states associate with lesion dynamics in multiple sclerosis (15')

    Session 4: Glial regulation of neuronal activity and synaptic plasticity[Maaszaal]
    Chairs: Nicky Scheefhals & Lot de Witte (Nijmegen)

    Jimena Baleriola  (Madrid, Spain) TBA (30')
    Mark Verheijen  (Amsterdam) Astrocyte-Synapse Structural Plasticity in Memory Function (15')
    Bas Lendemeijer  (Rotterdam) In vitro models to study human glial-neuronal interactions (15')
    Carlos González Jimémez  (Nijmegen) Microglial contributions to neural network dysfunction in Kleefstra Syndrome (15')
    Nicky Scheefhals  (Nijmegen) Better together: neuron-glia interactions shape synaptic maturation and plasticity in human iPSC-derived networks (15')

    Session 5: Beyond neurotransmission: Serotonin's role in brain development across species[Bloesem]
    Chairs: Judith Homberg & Sharon Kolk (Nijmegen)

    Francesca Calabrese  (Milan, Italy) Modulating the serotonergic system across generations: from mother to pup (30')
    Marta Samine  (Nijmegen) From neurodevelopment to behavior: impact of lifelong serotonergic dysregulation on prefrontal circuit maturation (15')
    Hannah El Marroun  (Rotterdam) Serotonin pathway-specific polygenic risk for psychiatric disorders and brain morphology in adolescents (15')
    Judith Homberg  (Nijmegen) Effect of maternal serotonergic genotype on offspring brain and behavioral development (15')
    Jocelien Olivier  (Groningen) The effects of cumulative early life stress on anxiety levels in male and female serotonin transporter knockout rats (15')

    Session 6: Development and modulation of hippocampal circuits[Royal Gala]
    Chairs: Suzanne van der Veldt (Groningen) & Freyja Ólafsdóttir (Nijmegen)

    Andrew MacAskill  (London, United Kingdom) Early life experience shapes hippocampal circuits for learning hidden rules (30')
    Guido Meijer  (Nijmegen) Same place, different context: dynamic switching between stimulus-outcome associations by the para-hippocampal network (15')
    Guillaume Etter  (Groningen) The preconfigured brain: How internal hippocampal sequences organize adult learning and memory (15')
    Freyja Ólafsdóttir  (Nijmegen) What can development tell us about the neuronal underpinnings of spatial memory? (15')
    Suzanne van der Veldt  (Groningen) Neuromodulatory tuning of hippocampal activity shapes defensive behavior (15')

    Session 7: Multi-domain lifestyle approaches in the prevention and treatment of Alzheimer’s Disease: insights from preclinical and clinical studies[Wijnkers]
    Chairs: Aniko Korosi & Emmy Hoeksema (Amsterdam)

    Evgenia Salta  (Amsterdam) Harnessing exercise to amend neuroinflammation in Alzheimer’s disease (30')
    Lianne Remie  (Nijmegen) The gut-immune-brain axis in cognitive aging: longitudinal evidence from a multidomain lifestyle intervention in older adults (15')
    Yannick Vermeiren  (Wageningen) Mediterranean-style diets and cognitive ageing: modulation of tryptophan metabolism in at-risk older adults (15')
    Emmy Hoeksema  (Amsterdam) Omega-3 interventions in Alzheimer’s Disease: where are we at? insights from clinical and preclinical studies (15')
    Niek Renckens  (Amsterdam) Microglia exhibit distinct morphological and phagocytic states depending on proximity to engram neurons and amyloid plaques (15')

    13:00 Lunch

    14:15 Parallel Sessions B
    Session 8: Synaptic plasticity mechanisms in learning and memory[Maaszaal]
    Chairs: Kubra Gulmez Karaca (Utrecht) & Janina Kupke (Amsterdam)

    Alessio Attardo  (Magdeburg, Germany) A new path towards the synaptic engram (30')
    Kubra Gulmez Karaca  (Utrecht) Time- and sex-dependent characterization of engram spine morphology in fear memory processing (15')
    Renee Pullen  (Amsterdam) From synapse structure to molecular identity: spatiomolecular mapping of mGluR5 in CA1 engram cell spines (15')
    Robbert Havekes  (Groningen) Reversing sleep loss-induced spatial and social amnesia (15')
    Thije Willems  (Amsterdam) GluA3 mediated synaptic mechanisms for memory consolidation during sleep (15')

    Session 9: Voltage-gated ion channels in health and disease[Wijnkers]
    Chairs: Marina Hommersom (Nijmegen) & Else Tolner (Leiden)

    Massimo Mantegazza  (Valbonne-Sophia Antipolis, France) Voltage‑gated sodium channels in neurological diseases: insights from genetic variants of NaV1.1/SCN1A (30')
    Maarten Kole  (Amsterdam) Beyond the node: voltage-gated channels and ion flow across the myelin landscape
      (15')

    Armagan Kocer  (Enschede) Decoding Dysfunction: How Inherited Mutations Alter Kv4.3 Channel Gating and Lead to Spinocerebellar Ataxia 19/22 (15')
    Marina Hommersom  (Nijmegen) Human neuronal networks on micro-electrode arrays as a tool to assess genotype-phenotype correlation in CACNA1A-related disorders (15')
    Else Tolner  (Leiden) Linking channelopathy-related mutations to neurophysiological mechanisms in migraine and epilepsy (15')

    Session 10: Individual differences in social behaviour and coping across species[Royal Gala]
    Chairs: Rixt van der Veen (Amsterdam) & Michael van der Kooij (Utrecht)

    Benjamin Jurek  (Munich, Germany) Observing mice at home: Long-term deep phenotyping of social behavioral traits in a home-cage setting (30')
    Jean-Christophe Billeter  (Groningen) Modulation of sleep by social experience in Drosophila Melanogaster (15')
    Lisa Bouwman  (Amsterdam) Coping is of the essence: Using a complexity approach to integrate different coping behaviors after early life stress (15')
    Bart Pollux  (Wageningen) The role of the placenta in transferring maternal stress to developing embryos: a comparison of livebearing fish species with and without placenta (15')
    Michael van der Kooij  (Utrecht) Coping early in life: Automated tracking of parental mice gives new directions into the underpinnings of early life stress (15')

    Session 11: Innovative iPS cell-derived neuronal models for translational therapy development[Bloesem]
    Chairs: Katrin Linda (Nijmegen) & Femke de Vrij (Rotterdam)

    Aleksandra Pękowska  (Warsaw, Poland) Astrocytes and the evolution of neuronal developmental tempo (30')
    Carles Calatayud Aristoy  (Leuven, Belgium) Electrophysiological mapping of human striatal microcircuits enables Parkinson's disease stratification (15')
    Katrin Linda  (Nijmegen) Advancing therapeutic insight with human iPS cell-derived neuron–astrocyte models (15')
    Dana Vervloet  (Rotterdam) Exploring the potential of antisense oligonucleotide therapy for a RASopathy using iPSC-based models. (15')
    Juliette Kamp  (Rotterdam) Investigating the therapeutic potential of SYNGAP1 splice-switching oligonucleotides (15')

    Session 12: Metabolic and environmental stressors at the roots of dementia[Tuin & Waterkers]
    Chairs: Sébastien Foulquier (Maastricht) & Martina Schmidt (Groningen)

    Emma Kasteel  (Utrecht) Plastic not-so-fantastic? Neurotoxic effects of micro- and nanoplastics in vitro (30')
    Kenneth Vanbrabant  (Hasselt, Belgium) Early-life air pollution exposure as a driver of later-life cognitive vulnerability (15')
    Martina Schmidt  (Groningen) Environmental stressors in experimental Alzheimer models (15')
    Amanda Kiliaan  (Nijmegen) Obesity and brain health (15')
    Sébastien Foulquier  (Maastricht) Cardiometabolic stressors as drivers of vascular cognitive impairment (15')

    Session 13: New crucial roles of neuroglial populations: insight from the glioma-induced changes[Pink Lady]
    Chairs: Lucas Baudouin (Amsterdam) & Marina Trombetta Lima (Groningen)

    David Ohayon  (Toulouse, France) Astrocyte heterogeneity and glioblastoma microenvironment (30')
    Alexandra de Reus  (Utrecht) The cellular landscape of the glioblastoma invasive front: uncovering mechanisms driving glioblastoma invasion in the tumor micro-environment (15')
    Marina Trombetta Lima  (Groningen) Reprogramming the tumor microenvironment through Matrix Metalloproteinase Inhibitors (15')
    Frank Kruyt  (Groningen) Identification of novel mechanisms regulating microtube-based cellular connectivity and tumor aggressiveness in glioblastoma (15')
    Lucas Baudouin  (Amsterdam) Multiscale analysis of cognitive impairment in IDH-mutant glioma: from connectome to oligodendrocyte dynamics (15')

    15:45 Coffee & Tea

    16:15 Plenary Session
    Session 14: Keynote Lecture
    Chair: Vanessa Donega (Amsterdam)

    Candida Snow  (Zwolle) Take off your culture glasses (45')

    17:15 Posters & drinks
    Session 15: Poster session 1

    18:30 Dinner

    20:00 Plenary Session
    Session 16: Award Ceremony

    21:00 Social

    Keynote Lecture

    Illuminating endocannabinoid action in neural circuits

    Building and leveraging large-scale single-cell censuses for neuroscience

    Glial regulation of neuronal activity and synaptic plasticity

    Beyond neurotransmission: Serotonin's role in brain development across species

    Development and modulation of hippocampal circuits

    Multi-domain lifestyle approaches in the prevention and treatment of Alzheimer’s Disease: insights from preclinical and clinical studies

    Synaptic plasticity mechanisms in learning and memory

    Voltage-gated ion channels in health and disease

    Individual differences in social behaviour and coping across species

    Innovative iPS cell-derived neuronal models for translational therapy development

    Metabolic and environmental stressors at the roots of dementia

    New crucial roles of neuroglial populations: insight from the glioma-induced changes

    Keynote Lecture

    Poster session 1

    Award Ceremony

  • 08:30 Registration (with Coffee & Tea)

    09:00 Parallel Sessions C
    Session 17: How positive and negative early life events shape food intake and related behaviors[Royal Gala]
    Chairs: Frank Meye & Gisela Lazzarino (Utrecht)

    Mark Rossi  (New Brunswick, NJ, USA) Rewiring of hypothalamic feeding circuits by early-life overnutrition (30')
    Hanneke van Santen  (Utrecht) Acquired hypothalamic dysfunction and its metabolic consequences (20')
    Natalia Schilder  (Amsterdam) The effects of oral tributyrin supplementation in a murine, double-hit model of depression (20')
    Gisela Lazzarino  (Utrecht) How early-life risky play opportunities influence prefrontal cortical circuits and inhibitory control over food reward seeking (20')

    Session 18: Patterns of divergence: Sex effects during brain development from cells to circuits[Bloesem]
    Chairs: Aleksandra Badura (Rotterdam) & Sam de Kater (Nijmegen)

    Gabriele Rune  (Berlin, Germany) Sex-specific regulation of neurosteroid synthesis by GnRH and its relevance for synaptic plasticity in the hippocampus (30')
    Joram Mul  (Amsterdam) Sex-dependent neurobiology of exercise training-induced stress resilience: a focus on ∆FOSB (15')
    Anna Sancho Balsells  (Amsterdam) Sex-specific effects of prenatal stress on fetal microglia (15')
    Stephanie Dijkhuizen  (Rotterdam) Sensory processing and cognitive impairments in people with SHANK2 loss of function mutations and in the SHANK2 haploinsufficient mutant mice   (15')
    Sam de Kater  (Nijmegen) Intrinsic properties of CA1 pyramidal cells are set by sex hormones in organotypic hippocampal slices from male and female mice (15')

    Session 19: Mitochondrial power failure: at the crossroad of environmental exposure and genetic susceptibility in brain pathologies[Tuin & Waterkers]
    Chairs: Amalia Dolga & Tingting Chen (Groningen)

    Janine Santos  (Durham, NC, USA) From screens to systems: discovering new roles for mitochondria in human health (30')
    Tingting Chen  (Groningen) PSEN1 ΔE9 NPC-Derived Extracellular Vesicles Induce Neural and Metabolic Impairments in Brain Organoids (15')
    Vedrana Stefanic  (Nijmegen) Abnormal synaptic transmission in mouse brain and human neuronal cell models of mitochondrial disease (15')
    Teresa Mitchell-Garcia  (Groningen) Exposure to diesel exhaust particles impairs the function of human iPSC-derived microglia with the LRRK2 G2019S mutation (15')
    Angelica Sabogal Guaqueta  (Amsterdam) Mitochondrial dysfunction as a mediator of heavy metal neurotoxicity in microglia. (15')

    Session 20: How omics studies can tell tales about the AD and FTD brain[Wijnkers]
    Chairs: Sabine Spijker & Roberta Giannelli (Amsterdam)

    Ehsan Pishva  (Maastricht) Large-scale multiomics investigation of cortical miRNA changes in Alzheimer's Disease (30')
    Roberta Giannelli  (Amsterdam) Multi-omics approach for defining the disease trajectory of FrontoTemporal Dementia (15')
    Guus Smit  (Amsterdam) The proteomic profile of Von Economo neurons  (15')
    Betty Tijms  (Amsterdam) Alzheimer's disease pathophysiological subtypes based on CSF proteomics have distinct CSF lipidomics profiles (15')
    Lynn van Olst  (Groningen) Alzheimer brain transcriptomics (15')

    Session 21: Spike fast, die young? Development, maturation, plasticity, dysfunction and decline of Parvalbumin-positive neurons and their Perineuronal Nets[Maaszaal]
    Chairs: Moritz Negwer & Corette Wierenga (Nijmegen)

    Monika Moissidis  (London, United Kingdom) A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons (15')
    Moritz Negwer  (Nijmegen) Whole-brain, three-dimensional visualization of parvalbumin neurons and perineuronal nets (15')
    Martijn Selten  (London, United Kingdom) Mechanisms of homeostatic regulation in PV interneurons (15')
    Ronald van Kesteren  (Amsterdam) Selective interneuron vulnerability in a mouse model of Alzheimer’s disease (15')
    Laure Verret  (Toulouse, France) The role of hippocampal parvalbumin neurons in memory deficits and functional recovery in Alzheimer’s models (30')

    Session 22: Antisense oligonucleotide therapeutics for brain disorders[Pink Lady]
    Chairs: Ronald Buijsen (Leiden) & Dana Vervloet (Rotterdam)

    Ype Elgersma  (Rotterdam) Developing Antisense Oligonucleotide (ASO) therapy for Neuordevelopmental Disorders: From proof of concept to clinical trials (30')
    Ronald Buijsen  (Leiden) How to synthesize ASOs? (15')
    Gijs-Jan Scholten  (Leiden) Allele-specific antisense oligonucleotides to treat Spinocerebellar Ataxia Type 1 (SCA1) (15')
    Inge Zuhorn  (Groningen) Cellular processing of delivery vehicles (15')
    Marjon Pasmooij  (Utrecht) Regulatory aspects of ASO therapeutics (15')

    10:30 Coffee & Tea

    11:00 Parallel Sessions D
    Session 23: Synaptic and network alterations in early Alzheimer's disease[Tuin & Waterkers]
    Chairs: Lucas Lumeij & Ronald van Kesteren (Amsterdam)

    Stefan Remy  (Magdeburg, Germany) Synaptic and network dysfunction in Alzheimer's disease (30')
    Zehra Kazmi  (Amsterdam / Nijmegen) Excitatory targets, inhibitory consequences: How amyloid-β oligomers tip the scales of network E/I balance during early Alzheimer’s disease (15')
    Lucas Lumeij  (Amsterdam) The role of AMPA receptor subunit GluA3 in amyloid-β-induced synaptic and network alterations in Alzheimer's disease (15')
    Kevin Marinus  (Amsterdam) Alzheimer-causing PSEN1 mutations interfere with early neuronal differentiation in a human iPSC-derived model for neurodevelopment (15')
    Anne van Nifterick  (Amsterdam) Unravelling hyperexcitability in Alzheimer's disease: towards non-invasive network markers  (15')

    Session 24: Intrinsic plasticity: shaping signals from input through output to circuits[Bloesem]
    Chairs: Ting-Feng Lin (Utrecht) & Maarten Kole (Amsterdam)

    Guillaume Drion  (Liège, Belgium) Cellular homeostasis and neuromodulation as core mechanisms of intrinsic plasticity and network function. (30')
    Zahra Hemmat  (Rotterdam) Cerebellar subpopulation-specific differences in intrinsic excitability and plasticity related to distinct movement kinematics (15')
    Roberto D’Angelo  (Utrecht) Social Stress and Dopamine Oppositely regulate Intrinsic Plasticity of Prefrontal Cortical Outputs to the Nucleus Accumbens and Basolateral Amygdala in the Regulation of Palatable Food Intake
      (15')

    Vasiliki Theodorou  (Amsterdam) Chronic network silencing triggers distinct AIS plasticity in excitatory and inhibitory neurons (15')
    Ting-Feng Lin  (Utrecht) Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum (15')

    Session 25: Human in vitro and primary tissue models of brain development and disease[Maaszaal]
    Chairs: Steven Sloan (Amsterdam) & Noelia Anton Bolanos (Utrecht)

    Debby Silver  (Durham, NC, USA) Building our brains: from development to evolution (30')
    Noelia Anton Bolanos  (Utrecht) Mirroring human Brain Development and Disease using Brain Organoids as Avatars (15')
    Femke de Vrij  (Rotterdam) Disease modeling using human adherent cortical organoids (15')
    Anna Pagliaro  (Utrecht) Deciphering mechanisms driving human brain development and expansion: insights from novel in vitro organoid systems (15')
    Evgenia Salta  (Amsterdam) Single-cell molecular mapping of human adult hippocampal neurogenesis in Alzheimer’s disease and resilience
      (15')


    Session 26: Neuromorphic computing[Wijnkers]
    Chairs: Arezoo Alizadeh (Nijmegen) & Mario Negrello (Rotterdam)

    Herbert Jaeger  (Groningen) A semantic theory of universal computation - why? therefore! (30')
    Chiara De Luca  (Zurich, Switzerland) Neuromorphic digital twins for closed-loop neurostimulation (20')
    Tim Kamsma  (Utrecht) Brain-inspired computing in a brain-inspired medium (20')
    Arezoo Alizadeh  (Nijmegen) Space-By-Time Semi-NMF: A Decomposition Approach for Single-Trial Neural Decoding (20')

    Session 27: Expanding dimensions of cAMP signaling: from spatial nanodomains to cell-wide integration[Pink Lady]
    Chairs: Melissa Schepers (Diepenbeek, Belgium) & Tim Vanmierlo (Maastricht / Hasselt, Belgium)

    Cécile Derieux  (Mainz, Germany) cAMP nanodomains and GPCR signaling (30')
    Rosa Randoe  (Amsterdam) GPCR signaling at astrocyte endfeet: GPRC5B and the biology of brain edema (15')
    Martina Schmidt  (Groningen) The Role of cAMP in Neurodegenerative Models (Eng) (15')
    Rob Leurs  (Amsterdam) Modulation of GPCR-based cAMP signalling with light (15')
    Tim Vanmierlo  (Maastricht / Hasselt, Belgium) cAMP Signaling as Hub and Driver in (re)Myelination (15')

    Session 28: Adaptive forgetting mechanisms: translational approaches across neuroscience disciplines[Royal Gala]
    Chairs: Conny Quaedflieg (Maastricht) & Kevin van Schie (Tilburg)

    Michael Anderson  (Cambridge, United Kingdom) Improving mental health by training the mechanisms of adaptive forgetting (30')
    Martyna Gwiazda  (Maastricht) Intentional suppression of memories consolidated under stress (20')
    Ralph Wientjens  (Amsterdam) Memory suppression versus Extinction: disentangling effects on memory content and emotional affect (20')
    Kevin van Schie  (Tilburg) Non-invasive brain stimulation to enhance individuals’ capacity to control intrusive memories (20')

    12:30 Lunch

    13:45 Plenary Session
    Session 29: Keynote Lecture
    Chair: Conny Quaedflieg (Maastricht)

    Michael Anderson  (Cambridge, United Kingdom) Adaptive forgetting for mental health (45')

    14:45 Coffee & Tea

    15:15 Parallel Sessions E
    Session 30: Rebalancing neuroscience: revealing sex-dependent mechanisms in health and disease[Maaszaal]
    Chairs: Sabine Spijker & Sophie van der Sluis (Amsterdam)

    Sofie Valk  (Düsseldorf, Germany) Spatiotemporal axes of brain organisation to understand health and disease (30')
    Anne Marije Kaag  (Amsterdam) The influence of ovarian hormones on the neural mechanisms underlying addiction (15')
    Cato Romero  (Amsterdam) Sex differences in genetic pathways underlying ischaemic heart disease–depression comorbidity (15')
    Lin Zhang  (Amsterdam) Sex differences in the cholinergic system in depression and suicide (15')
    Sabine Spijker  (Amsterdam) Diversity in depression-induced proteomic signatures (15')

    Session 31: Dynamics of blood vessels in the maturing brain: mechanisms of formation, repair and communication with neurons[Wijnkers]
    Chairs: Carla Gomes da Silva (Utrecht) & Amparo Acker Palmer (Frankfurt, Germany)

    Amparo Acker Palmer  (Frankfurt, Germany) Angioneurins orchestrate neurovascular development and circuit formation (30')
    Carlos Flores Clara  (Utrecht) New mechanisms of glia-mediated vascular repair during brain development (20')
    Henrique Nogueira Pinto  (Amsterdam) From stem cells to neurovascular networks: Building a functional human blood-brain barrier in vitro (20')
    Tommaso Ristori  (Eindhoven) Integrating experiments with simulations to unravel pathological angiogenesis (20')

    Session 32: Shared and distinct mechanisms in synucleopathies and tauopathies: synergistic to solutions  (hosted by Alzheimer Nederland and ParkinsonNederland)[Pink Lady]
    Chairs: Wiep Scheper & Wilma van de Berg (Amsterdam)

    Wiep Scheper  (Amsterdam) Neuronal resilience to tau and α-synuclein pathology: shared mechanisms and opportunities (15')
    Marcel Verbeek  (Nijmegen) What body fluid biomarkers can tell learn us about overlap and differences in neurodegenerative disorders (15')
    Wilma van de Berg  (Amsterdam) Neuropathological evidence of co-pathologies in synucleinopathies (15')
    Bart Eggen  (Groningen) Microglia heterogeneity across neurodegenerative disorders (15')
    Panel discussion with the speakers incl. questions from the audience (30')

    Session 33: Modeling iPSC-Microglia: insights & communication (MIMIC-NL)[Royal Gala]
    Chairs: Lot de Witte (Nijmegen) & Amalia Dolga (Groningen)

    Šárka Lehtonen  (Kuopio, Finland) Multiscale Modeling of Human Microglia in Synucleinopathies: From Cellular States to Organoid and In Vivo Neurodegeneration (30')
    Lot de Witte  (Nijmegen) Advancing insights into microglial responses to neuronal hyperexcitability using iPSC models (15')
    Renata Baptista Vieira de Sa  (Amsterdam) Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids (15')
    Kim Kleijn  (Amsterdam) iPSC-derived microglial interferon states in drug screening for Alzheimer’s disease (15')
    Amalia Dolga  (Groningen) Human iPSC-derived microglia change the cellular metabolic profile of the brain organoids (15')

    Session 34: The Locus Coeruleus across states: noradrenergic modulation from synapses to behavior[Bloesem]
    Chairs: Danai Riga & Helmut Kessels (Amsterdam)

    Jordan McCall  (St. Louis, MO, USA) Parsing pain and aversion in the locus coeruleus noradrenergic system (30')
    Helmut Kessels  (Amsterdam) Effects of noradrenaline signaling on synaptic plasticity  (15')
    Danai Riga  (Amsterdam) Deciphering the neural footprints of physical and emotional adversity (15')
    Alejandro Osorio-Forero  (Amsterdam) The locus coeruleus across vigilance (15')
    Lukas van Herk  (Utrecht) Pharmacologically induced stress affects moral decision-making, working memory, and risk-taking in military personnel (15')

    Session 35: Integrative computational neuroscience: from deep learning to spikeing and data-driven approaches[Tuin & Waterkers]
    Chairs: Ellen Boven & Zhenyu Gao (Rotterdam)

    Loreen Hertäg  (Berlin, Germany) Modelling prediction errors: from neurons to circuits to cortical layers (30')
    Jorge Mejías  (Amsterdam) Biological architectures for predictive coding (15')
    Heike Stein  (Paris, France) Reconstructing the dynamics of locomotion explains the emergence of coordinated gaits on structured surfaces in mice (15')
    Fleur Zeldenrust  (Nijmegen) Heterogeneity in the brain: lessons from theory and experiment
 (15')
    Pedro Gonçalves  (Leuven, Belgium) Machine learning for mechanistic insight in neuroscience (15')

    16:45 Posters & drinks
    Session 36: Poster session 2

    18:00 Closure DNM 26 & poster prizes

    How positive and negative early life events shape food intake and related behaviors

    Patterns of divergence: Sex effects during brain development from cells to circuits

    Mitochondrial power failure: at the crossroad of environmental exposure and genetic susceptibility in brain pathologies

    How omics studies can tell tales about the AD and FTD brain

    Spike fast, die young? Development, maturation, plasticity, dysfunction and decline of Parvalbumin-positive neurons and their Perineuronal Nets

    Antisense oligonucleotide therapeutics for brain disorders

    Synaptic and network alterations in early Alzheimer's disease

    Intrinsic plasticity: shaping signals from input through output to circuits

    Human in vitro and primary tissue models of brain development and disease

    Neuromorphic computing

    Expanding dimensions of cAMP signaling: from spatial nanodomains to cell-wide integration

    Adaptive forgetting mechanisms: translational approaches across neuroscience disciplines

    Keynote Lecture

    Rebalancing neuroscience: revealing sex-dependent mechanisms in health and disease

    Dynamics of blood vessels in the maturing brain: mechanisms of formation, repair and communication with neurons

    Shared and distinct mechanisms in synucleopathies and tauopathies: synergistic to solutions  

    Modeling iPSC-Microglia: insights & communication (MIMIC-NL)

    The Locus Coeruleus across states: noradrenergic modulation from synapses to behavior

    Integrative computational neuroscience: from deep learning to spikeing and data-driven approaches

    Poster session 2

    • Thursday .::. 25 June, 17:15


      P1.1  The translation-dependent neuronal ER proximity proteome reveals novel candidate proteins regulating subcellular translation in neurons
      Vivienne Aline Bauer (Leiden)

      P1.2  Zebrafish Fignl1 regulates the Slit/Robo pathway, required for retinal axon guidance
      Naomi Berbée (Amsterdam)

      P1.3  From mouse models to human blood: early‑life stress‑induced mitochondrial dysfunction as a translational marker of Alzheimer’s disease
      Anne Bissay (Amsterdam)

      P1.4  Roles of ER–Golgi contact sites on polarized protein trafficking in neurons
      Dilixiati Dilikaibier (Utrecht)

      P1.5  Beyond bradychrony: species-divergent dendritic maturation and synaptic function in great ape iNeurons
      Max Sterling (Nijmegen)

      P1.6  Establishing an organotypic hippocampal slice model to study astrocyte–synapse interactions
      Imane Al Idrissi (Almere)

      P1.7  Effect of sleep deprivation on hippocampal synaptic plasticity: a SABV approach
      Elena Ascension Horcas (Groningen)

      P1.8  Region and age-related microglia heterogeneity in the healthy human brain
      Anouck Bahnerth (Amsterdam)

      P1.9  Investigating the role of SHANK in mPFC engram cells on synaptic connectivity and memory retrieval
      Indy Batteram (Amsterdam)

      P1.10  The intracellular molecular mechanisms underlying GluA3-containing AMPA-receptor plasticity
      Iris Berden (Amsterdam)

      P1.11  Association between dendritic morphology and subthreshold signal propagation in mouse and human cortical layer 2 & 3 pyramidal neurons
      Nicolás Beyer Diaz-Guardamino (Amsterdam)

      P1.12  Expanding the tripartite synapse
      Thomas Blok (Amsterdam)

      P1.13  Assessing neuronal plasticity in the mPFC after cannabis exposure using ImageJ
      Aileen Blom (Utrecht)

      P1.14  Grasping the structural astrocyte-synapse interaction in early Alzheimer’s disease with AstroGRASP
      Cristina Boers Escuder (Amsterdam)

      P1.15  EPSP propagation speed in human cortical neurons
      Tom Coopmans (Amsterdam)

      P1.16  Keep the balance: chronic silencing triggers different AIS adaptations in excitatory and inhibitory neurons
      Ana Rita da Cunha (Amsterdam)

      P1.17  From SNAREs to signals: deciphering the exocytic machinery controlling ion channels at the axon initial segment
      Lukas de Haas (Amsterdam)

      P1.18  Neurobiological consequences of chronic sleep loss: hippocampal neuronal plasticity and BDNF-signaling
      Nienke de Vries (Groningen)

      P1.19  Microglial regulation of memory engram stability in Alzheimer’s Disease: spatial and activity-dependent mechanisms
      Evie de Wijs (Amsterdam)

      P1.20  The local role of cell death proteins in inhibitory synapse elimination
      Troy Kapteijns (Nijmegen)

      P1.21  Effects of Camk2a and Camk2b double knockout on neuronal excitability in hippocampal neurons
      Nadine Maas (Rotterdam)

      P1.22  Species-specific astrocytic specialization and glutamate clearance kinetics in human and mouse neocortex
      Bianca Marin (Amsterdam)

      P1.23  Interplay between axon initial segment geometry and somatodendritic characteristics shape action potential initiation in human layer 2/3 pyramidal neurons
      Hanna Marteijn (Amsterdam)

      P1.24  High-resolution spatiomolecular mapping of CA1 engram cell synapses
      Renee Pullen (Amsterdam)

      P1.25  Subtype-specific regulation of metabotropic glutamate receptor surface mobility links spatial organization to receptor function
      Dimitrios Samouil (Amsterdam)

      P1.26  Nanoscale organisation and mobility of metabotropic glutamate receptors
      Archit Singh (Amsterdam)

      P1.27  Beyond protein abundance: synaptic phosphoproteomic signatures of contextual fear memory
      Kim Verdaasdonk (Amsterdam)

      P1.28  Noelin as a molecular regulator of synapse-specific AMPA receptor organization
      Rozanne Voorvelt (Amsterdam)

      P1.29  Effects of developmental and epileptic encephalopathy-associated gene, AP2M1, on synaptic transmission in human iPSC-derived neurons 
      Varvara-Maryia Zlotnik (Amsterdam)

      P1.30  Investigating EV-miRNA-regulated inflammatory and stress pathways in SARS-CoV-2–associated neurodegeneration
      Gunjan Bawne (Rijswijk)

      P1.31  From neuroinflammation to neuroprotection: TNFR2 agonist treatment in a mouse model of Alzheimer’s disease
      Irem Bayraktaroglu (Groningen)

      P1.32  Investigating the efficacy of a novel TNFR2 agonist in male AD mice
      Ruben Blaak (Groningen)

      P1.33  The effects of early handling and sex on Alzheimer’s disease-related pathologies in 6-month-old APP/PS1 mice
      Alise Bobkova (Amsterdam)

      P1.34  Exploring the neuroprotective role of extracellular vesicles against ferroptosis-mediated neurodegeneration
      Daria Costache (Groningen)

      P1.35  The effect of progranulin loss on neuronal secretory autophagy
      Fleur de Jager (Utrecht)

      P1.36  Visual evoked potentials enable longitudinal monitoring of remyelination in chronic EAE
      Zoë Donders (Maastricht)

      P1.37  The effect of presenilin loss on neuronal secretory autophagy
      Arana Erken (Utrecht)

      P1.38  Unraveling the role of C9ORF72 using iNeurons
      Larissa Goes (Utrecht)

      P1.39  Using patient-derived PSEN1-mutant iPSCs to model excitation/inhibition imbalance in Alzheimer’s disease
      Tasha Ibrahim (Amsterdam)

      P1.40  Characterization of hippocampal pathology in a leptomeningeal inflammation model of Multiple Sclerosis
      Ilina Ilieva (Amsterdam)

      P1.41  Assessing neuroinflammation and repair after TNFR2 agonist treatment in aged multiple sclerosis
      Alie-Yke Jonkman (Groningen)

      P1.42  Exploring the effect of a novel TNFR2 agonist on motor functions and mechanical allodynia in an aging MS model
      Mariëlle Kuipers (Groningen)

      P1.43  Is it ever too early to start to worry? Investigating the effects of early life stress combined with social stress later in life on neuroinflammation and Alzheimer’s disease
      Giulia Mozzanica (Groningen)

      P1.44  Selective TNF receptor 2 activation alleviates inflammation and neurological deficits in Multiple Sclerosis
      Natalia Ortí Casañ (Groningen)

      P1.45  Microglia exhibit distinct morphological and phagocytic states depending on proximity to engram neurons and amyloid plaques
      Niek Renckens (Amsterdam)

      P1.46  Interactive effects of artificial light at night and 3xTg-AD genotype on circadian rhythmicity and Alzheimer’s disease markers
      Anuja Rui (Groningen)

      P1.47  Investigating the link between SARS-CoV-2 and Parkinson’s Disease using patient-derived midbrain organoids
      Matilde Ruo (Amsterdam)

      P1.48  Capturing the neurovascular-immune interface in Alzheimer’s disease
      Sofie Schuringa (Groningen)

      P1.49  Piecing Cornelia de Lange syndrome together: one mosaic brain organoid at a time
      Marieke Alzeer (Rotterdam)

      P1.50  Tg-mediated roles in sleep/memory, & different monoamine transporters
      Carolina Antunes Pereira (Nijmegen)

      P1.51  Deciphering blood-brain barrier contributions to sleep disturbances in autism spectrum disorder
      Theodóra Ægisdóttir (Nijmegen)

      P1.52  The neurodevelopmental disorder-associated CAMK2A-Thr286Pro variant leads to severe molecular, behavior, and synaptic plasticity deficits in mice
      Jaime Borregon Jimenez (Rotterdam)

      P1.53  Peroxisomes: the forgotten organelle
      Juliette Chevalier (Amsterdam)

      P1.54  FoxP regulates systemic metabolic rate and sleep stability via repression of the mitochondrial enzyme Pepck2 in Drosophila
      Melanie de Wit (Nijmegen)

      P1.55  Monoaminergic regulation of sleep and memory in Drosophila melanogaster
      Madilyn Ghai (Nijmegen)

      P1.56  Roles of monoamine transporters and receptors in sleep/memory using Drosophila melanogaster
      Eline Hamersma (Nijmegen)

      P1.57  Two genotypes, one brain: modeling mosaic Cornelia de Lange Syndrome using patient-derived cortical brain organoids
      Amber Hof (Rotterdam)

      P1.58  Advancing neurodevelopmental disorder therapy through mechanistic insights of antisense oligonucleotide
      Qianjun Ma (Rotterdam)

      P1.59  Axiomer™ mediated RNA editing of premature termination codon results in functional correction in MECP2 for Rett syndrome
      Marko Potman (Leiden)

      P1.60  ERASOR: a platform to design and select antisense oligonucleotides for personalized treatment of neurodevelopmental disorders
      Thierry Roob (Rotterdam)

      P1.61  Molecular mechanisms underlying RHOBTB2-related neurodevelopmental disorders and exploring its therapeutic potential
      Salma Sennouni (Rotterdam)

      P1.62  Defining RNF12 function in the X-linked neurodevelopmental disorder Tonne-Kalscheuer syndrome
      Kyra Swildens (Rotterdam)

      P1.63  Designing a broadly applicable ASO therapy for SYNGAP1 disorders
      Jip van den Hooff (Rotterdam)

      P1.64  UBE3A-neighbouring genes on chromosome 15q contribute to Angelman syndrome phenotype
      Amy van Hattem (Rotterdam)

      P1.65  Modelling CDKL5 deficiency disorder in a human in vitro neuronal model
      Xiuming Yuan (London, United Kingdom)

      P1.66  Finding the sweet spot: a comparative evaluation of antibiotic regimens for microbiome depletion in rats prior to FMT
      Maria Aydin (Nijmegen)

      P1.67  Effects of mindfulness training on self-referential processing in help-seeking youth with internalizing symptoms: behavioural and neural evidence from the PRYME trial
      Judith Bläsing (Nijmegen)

      P1.68  Neurobiology of mitochondria, miRNA-132 and perineuronal nets in the human nucleus basalis of Meynert in relation to depression and suicide
      Eleni Bovali (Amsterdam)

      P1.69  Chronic restraint stress and whole-body metabolism: insights from ventral hippocampus and hypothalamus
      Paola Brivio (Milan, Italy)

      P1.70  Hypothalamic ensembles driving maladaptive behaviour in the activity-based anorexia model
      Eileen Brouwer (Utrecht)

      P1.71  Effects of time-of-day dependent esketamine administration on circadian rhythmicity in wistar-kyoto rats
      Simone Cidoni (Groningen)

      P1.72  A proteomics approach to CNV mouse models in understanding affected molecular and cellular pathways in schizophrenia
      Suchita Reddy Enugala (Amsterdam)

      P1.73  Gender differences in alcohol-cue reactivity: the role of childhood trauma
      Alexandru-Constantin Hanches (Amsterdam)

      P1.74  Minocycline disrupts cocaine- but not predator odour-related memory reconsolidation: sex-specific behavioural responses to predatory threat
      Lara Loermans (Nijmegen)

      P1.75  Mapping neuronal ensembles during binge eating in the ventral tegmental area in an anorexia nervosa-like context
      Demi Pastoor (Utrecht)

      P1.76  Characterizing ventral tegmental area neuronal ensembles in stress-induced binge eating
      Anne van Oosterhout (Utrecht)

      P1.77  Guts2Beat depression: microbial metabolites from patients with depression to counteract cellular stress in microglia-containing cortical organoids
      Rivka Vollebregt (Amsterdam)

      P1.78  Time-of-day dependant effects of esketamine on circadian rhitmicity in a rat model of depression
      Jasper Wannet (Groningen)

      P1.79  From microbes to mood: piloting a human-to-rat FMT model to explore gut–brain molecular pathways and behavioral phenotypes
      Lotte Wekking (Nijmegen)

      P1.80  2P-imaging of inhibitory interneurons response patterns to electrical microstimulation for cortical visual restoration
      Isabella Andersen (Amsterdam)

      P1.81  Neuromodulation of inhibitory bouton formation via PKA
      Ségolène Bompierre (Nijmegen)

      P1.82  Non-polio enterovirus A71 and D68 infection of human neuromuscular organoids reveals distinct mechanisms of neuromuscular impairment
      Renata Baptista Vieira de Sa (Amsterdam)

      P1.83  Love at first hearing? Tracking female zebra finch representations of the male's song through pair-bonding using calcium imaging
      Ilse Bakker (Groningen)

      P1.84  Wired for company: gating of social experience by the circadian clock in Drosophila melanogaster females
      Vasileios Kapantaidakis (Groningen)

      P1.85  Whole-brain gene expression and neuronal activity at cellular resolution in behaving zebrafish
      Emmanuel Marquez Legorreta (Utrecht)

      P1.86  Decoding sleep and wakefulness from chronically implanted intracortical signals in a communication brain-computer interface user
      Elena Offenberg (Utrecht)

      P1.87  Genetic basis of natural variation in sociability
      Fiete Schritt (Groningen)

      P1.88  Human-specialised subthreshold resonance in cortical interneurons driven by subthreshold currents
      Sarah Scott (Amsterdam)

      P1.89  Activation of D2-expressing medium spiny neurons in the nucleus accumbens core mirrors the delaying effect of novelty exposure on feeding onset in rats
      Astrid van Irsen (Amsterdam)

      P1.90  A neural symphony: DRD1 neurons in the central clock orchestrate sleep and autonomic balance in rats
      Vanessa Veronica (Amsterdam)

      P1.91  The effects of glucocorticoids on remote memory and engram formation
      Tamara Versluis (Amsterdam)

      P1.92  Joint dopamine and serotonin dynamics in adaptive learning
      Beatriz de Carvalho (Amsterdam)

      P1.93  CADM2 overexpression in the medial prefrontal cortex of female mice: effects on alcohol self-administration and cue-induced relapse
      Irene Dolfini (Amsterdam)

      P1.94  Chemogenetic activation of medial amygdala dopamine receptor D1+ neurons transiently improves glucose response
      Roberta Tandari (Amsterdam)

      P1.95  The role of GluA3 on network synchrony and memory consolidation
      Zerra Blok (Amsterdam)

      P1.96  Mindfulness-based intervention and the relationship between Internalizing symptoms and Pavlovian-to-instrumental transfer in youth
      Myrthe Brouwer (Nijmegen)

      P1.97  Patterns of decline: sex differences in the onset of cognitive deficit in TgF344 rat model of Alzheimer’s disease
      Julia Burgos Flores (Groningen)

      P1.98  The impact of early-life cannabis exposure on social play behaviour and cognitive control in rats
      Sem Harder (Utrecht)

      P1.99  Mapping emotional stress: differential spatio-temporal encoding within key nodes of the stress-coping network
      Tudor Ianovici (Amsterdam)

      P1.100  Dissociating gonadal and chromosomal sex effects on memory after circadian disturbance
      Amber Kal (Groningen)

      P1.101  Cumulative stress and cognitive ageing: insights from population cohorts and a translational framework
      Jiahao Li (Groningen)

      P1.102  Spatial memories unlocked – reversing sleep deprivation-induced amnesia in female mice
      Suzanne Lunshof (Groningen)

      P1.103  Do I know you? Retrieving sleep deprivation-induced amnesia in social memory in female mice
      Giorgia Marrone (Groningen)

      P1.104  Supplementation of seaweed extracts to the diet reduces symptoms of Alzheimer’s Disease in the APPswePS1ΔE9 mouse model
      Nikita Martens (Rotterdam)

      P1.105  Temporal dynamics of Atf3 expression in learning and memory
      Sandra Parisi (Amsterdam)

      P1.106  Memory under stress: dissecting the role of engram cells and glucocorticoids in memory generalization
      Arianna Riera-Llobet (Amsterdam)

      P1.107  An SABV and translational perspective on the consequences of poor sleep on hippocampal function
      Li-Yan Sijbolts (Groningen)

      P1.108  Is it you my friend? Effects of sleep deprivation on memory engram encoding multiple social experience
      Caterina Stacchiola (Groningen)

      P1.109  Structural plasticity of fear memory engram across time and sex
      Noor van den Heuvel (Utrecht)

      P1.110  Observational learning of prey capture learning in a rat model of autism
      Lucas Wahl (Waltham, MA, USA)

      P1.111  Expression of the immediate early gene ATF3 in memory-related limbic regions following contextual fear conditioning
      Fiona Woolf Moñino (Amsterdam)

      P1.112  Looking beyond the diffraction limit: developing single-molecule microscopy approaches to resolve nanoscale structures in brain tissue
      Giulia Anderson (Amsterdam)

      P1.113  VoltZilla: an integrated software for real-time voltage imaging and feedback control
      Hunor Bartalis-Szélyes (Rotterdam)

      P1.114  Optimizing spatiomolecular mapping of synaptic subpopulations
      Arend Breukelaar (Utrecht)

      P1.115  Lab on a breadboard: a fully automated setup for hands-free longitudinal calcium imaging recordings
      Massimiliano Coscia (Groningen)

      P1.116  Benchmarking organoid dissociation strategies for single-nucleus transcriptomics profiling
      Emily Farrugia (Groningen)

      P1.117  Detection of subcompartment-specific proteomes in astrocytes
      Anna Gradl (Amsterdam)

      P1.118  Developing acute and robust re-localization tools to unravel the function of ER cisternae in dendrites
      Daphne Jager (Utrecht)

      P1.119  A versatile miniature two-photon microscope enabling multicolor deep-brain imaging
      Richard Kozma (Nanjing, China)

      P1.120  An affordable smoke delivery system for the inhaled administration of combusted or vaporized cannabis to rodents
      Thijs Messing (Utrecht)

      P1.121  SINEUP-mediated enhancement of Kv7.2 translation: development and in vitro validation
      Inez van Wijk (Amsterdam)

      P1.122  An analysis pipeline for single molecule imaging of endogenous synaptic proteins in brain tissue
      Bram Willems (Amsterdam)

    • Friday .::. 26 June, 16:45


      P2.1  Expansion microscopy reveals vascular damage sensing progenitors in the developing cortex
      Anna Alikhanbeigi (Utrecht)

      P2.2  ER cisternae-microtubule interactions regulate dendrite development
      Semanti Das (Utrecht)

      P2.3  The effect of in utero exposure to THC on the development of midbrain dopaminergic neurons
      Susanne Hazenberg (Amsterdam)

      P2.4  Autonomic innervation on a chip: from brainstem to cardiac muscle
      Marthe Kaal (Enschede)

      P2.5  Functional connectivity changes during the menopausal transition
      Bernardo Maciel (Amsterdam)

      P2.6  Mind the VAP: how endoplasmic reticulum contact sites regulates axonal mRNA localization
      Adriana Poza Rodríguez (Utrecht)

      P2.7  Marked by early life stress: increased levels of MMP8+ cells in the hippocampus
      Martin van der Jagt (Utrecht)

      P2.8  Lipid raft restricted second messenger signalling and membrane trafficking in Ephrin-A5–mediated axon guidance
      Ethan Wickens (Amsterdam)

      P2.9  Elucidating the protein interactome at ER-organelle contact sites
      Meizhen Xie (Utrecht)

      P2.10  From body parts to behaviour: automated tracking of dams exposed to early life stress
      Martijn Zegelaar (Utrecht)

      P2.11  Localisation of a protein complex regulating fluid homeostasis in astrocyte endfeet in models for megalencephalic leukoencephalopathy with subcortical cysts
      Felix Blokbergen (Amsterdam)

      P2.12  Region and age-related microglia heterogeneity in the healty human frontal cortex
      Pietro Colombo (Amsterdam)

      P2.13  ER cisternae and tubules cooperatively support dendritic spine growth during synaptic activity
      Koen Couperus (Amsterdam)

      P2.14  Resolving how interactions between the post-synaptic density and the actin cytoskeleton drive activity-dependent reorganization of the synapse at the nanoscale
      Diaz Danko (Amsterdam)

      P2.15  The glial side of stress: investigating astrocyte and microglial dynamics in trauma susceptibility
      Sandra de Mooij (Nijmegen)

      P2.16  Activity-driven axonal plasticity in parvalbumin interneurons
      Blaire Japhet Domingo (Amsterdam)

      P2.17  Functional impact of GluN2B-NMDAR LoF variants on developing neural networks in vitro
      Sophie Lee (Amsterdam)

      P2.18  The effect of norepinephrine on cAMP-PKA signaling in inhibitory hippocampal interneurons
      Bart Lelie (Nijmegen)

      P2.19  Ictal phase–amplitude coupling tracks hippocampal epileptogenesis
      Zhongyi Li (Rotterdam)

      P2.20  Characterizing microglia morphology 3 hours after LPS stimulation
      Fee Offerman (Amsterdam)

      P2.21  Dopaminergic stimulation drives inhibitory bouton formation via PKA activity
      Cathal Rollins (Nijmegen)

      P2.22  Characterisation of dendritic and axonal arborisation of the cortical chandelier cell
      Johanna Seemann (Amsterdam)

      P2.23  Resolving the nanoscale organization of AMPA receptor auxiliary subunits in the synapse
      Lieke Steijvers (Amsterdam)

      P2.24  Investigating the emergence of functional neuronal networks in the absence of developmental activity
      Lena Teunissen (Nijmegen)

      P2.25  Sex-dependent effects of testosterone on intrinsic and network properties of excitatory CA1 hippocampal neurons
      Tessa Tuinzaad (Nijmegen)

      P2.26  Development of a rapid and reversible degradation system for synaptic actin-regulating proteins
      Ruben van Amerom (Amsterdam)

      P2.27  Towards an in vitro model to study mechanisms of astrocyte-synapse interactions
      Marleen van den Munkhof (Amsterdam)

      P2.28  Energetic constraints of human L2/3 pyramidal neurons during sustained high-frequency activity
      Imme van der Knaap (Amsterdam)

      P2.29  Understanding the molecular mechanisms underlying astrocyte endfeet dynamics
      Eva van der Meer (Amsterdam)

      P2.30  The effect of Gi- and Gq-protein coupled receptor activation on inhibitory bouton dynamics in the mouse hippocampal CA1 region
      Floor van Heijnsbergen (Nijmegen)

      P2.31  Molecular and functional identification of CD200-CD200R interactions in neuron-glia signaling
      David van Lee (Amsterdam)

      P2.32  Cellular mechanisms setting local rules of spike-timing dependent plasticity
      Robin Weiler (Amsterdam)

      P2.33  The AIS at the nanoscale: linking cytoskeleton remodelling to re-distribution of voltage-gated ion channels during acute AIS plasticity
      Noémie Zerrouki (Amsterdam)

      P2.34  Dissecting the role of skeletal muscle in TDP-43-associated ALS
      Maja Anuszewska (Nijmegen)

      P2.35  Study of the mitochondrial malate-aspartate shuttle in Dars1 and Dars2 mouse model of leukoencephalopathies
      Olivia Belt (Amsterdam)

      P2.36  Investigation of neurons in the suprachiasmatic nucleus in postmortem brain of people with type 1 Diabetes Mellitus
      Tara Brinker (Amsterdam)

      P2.37  Investigating molecular pathways involved in hippocampal synaptic potentiation using advanced optic tools
      Andrea Caldarola (Amsterdam)

      P2.38  Effects of early-handling and sex on cognitive resilience in APP/PS1 mice
      Maria Carrigan (Amsterdam)

      P2.39  The effect of γ-secretase activity on lipid metabolism in ESC/iPSC-derived oligodendrocytes
      Antonia Coman (Amsterdam)

      P2.40  Are SARS_CoV-2 and Parkinson's disease connected?
      Anouk Dijkstra (Rijswijk)

      P2.41  The transcriptomic landscape of xenografted human microglia and their cellular interactions in Alzheimer’s disease
      Beáta Gaálová (Groningen)

      P2.42  Extracellular vesicles mediate a neuroprotective effect in PINK1 knockout neural progenitor cells under mitochondrial-induced stress
      Saskia Gooijer (Groningen)

      P2.43  Effects of an early-life ω-3 PUFA dietary intervention on lipidomic profiling in cortex and hippocampus of APP/PS1 and wild-type mice
      George Hogenboom (Amsterdam)

      P2.44  Predicting Alzheimer’s disease from human EEG signals
      Sara Juganaru (Groningen)

      P2.45  Supporting the oligodendrocyte-neuron coupling: pulling back the curtain on downstream PDE4D signalling
      Freddy Leenders (Maastricht)

      P2.46  A phage-based platform for the detection and targeting of amyloid-β oligomers in Alzheimer’s Disease
      Alexandre Lima (Amsterdam)

      P2.47  Microglial GABAB signaling links parvalbumin interneuron hyperactivity to synaptic pathology in AppNL-G-F alzheimer mice
      Teun Meere (Amsterdam)

      P2.48  Effects of early handling and sex on Alzheimer’s disease pathology in 12-month-old APP/PS1 mice
      Olga Minko (Amsterdam)

      P2.49  Early-life dietary enrichment with n-3 PUFAs shows no detectable effect on amyloid pathology in female APP/PS1 mice at 6 months of age
      Joanna Ñañez (Amsterdam)

      P2.50  Analysis of the mitochondrial electron transport chain in the central nervous system of  Dars2 mutant mice
      Sara Nulli (Amsterdam)

      P2.51  Development of an AAV-mediated α-synuclein non-human primate model of Parkinson’s disease
      Erik Nutma (Rijswijk)

      P2.52  Unravelling how loss of fumarase 1 function triggers adult-onset neurodegeneration 
      Müjgan Özcan (Nijmegen)

      P2.53  Isolating GFP+ neural stem cells from the neurogenic niches of mesenchymal stem cell-treated hypoxic-ischemic mice
      Suzanne Paauw (Utrecht)

      P2.54  Longitudinal multilevel EEG markers of dynamic network reorganization after mild traumatic brain injury: evidence from neural criticality and delta-band connectivity
      Sofie Paludanus (Den Haag)

      P2.55  Tau aggregation causes selective dendrite loss in iPSC-derived human neurons
      Robin Pelle (Amsterdam)

      P2.56  APOE4-driven astrocyte senescence as a contributor to Alzheimer’s disease pathology
      Jennet Pirkuliyeva (Amsterdam)

      P2.57  EEG-based biomarkers of anti-seizure medication efficacy in patients with refractory focal epilepsy
      Zoë Thépass (Leiden)

      P2.58  AAV-mediated elevation of glycyl-tRNA levels reverses peripheral neuropathy in mouse models of GARS1-associated Charcot-Marie-Tooth disease
      Kes van Blitterswijk (Nijmegen)

      P2.59  Consequences of artificial light at night on hippocampal memory in 3xTg-AD male and female mice
      Rianne van Dekken (Groningen)

      P2.60  Deep brain stimulation mechanisms in Parkinson’s disease via voltage imaging
      Maxime van Veghel (Rotterdam)

      P2.61  Cholinergic neurons in the nucleus basalis of meynert in prader-willi syndrome
      Anne Sophie Versteegh (Amsterdam)

      P2.62  Oxidative stress induces the integrated stress response in human astrocytes
      Saloua Zekri (Amsterdam)

      P2.63  PINK1 modulates diesel exhaust particle-induced dysfunction in human iPSC-derived microglia
      Leshan Zhang (Groningen)

      P2.64  The effect of PTPA variants on neuronal function and α-synuclein phosphorylation in Parkinson’s disease
      Irina Zogina (Rotterdam)

      P2.65  M13 bacteriophage to quantify changes in amyloid-β oligomer load following an immune challenge in APP/PS1 mice
      Verena Zwetsloot (Amsterdam)

      P2.66  Establishing hiPSC-derived 2D and 3D neuron-astrocyte models to study CACNA1A-related neuronal network activity
      Neslihan Akbulut (Nijmegen)

      P2.67  Physiological alterations underlying attack susceptibility in the D801N AHC mouse model
      Zoë Bor (Leiden)

      P2.68  Whole-brain cellular mapping of sex-specific system-level organization in autism spectrum disorder
      Jeske Enzerink (Nijmegen)

      P2.69  Understanding soma-restricted distribution of CAMK2G variants associated with neurodevelopmental disorders
      Maike Hinrichs (Rotterdam)

      P2.70  Markerless pose estimation and post-tracking behavioral phenotyping to assess the effect of early life stress and adult complex housing on stress response and social behavior in mice
      Yasin Karyagdi (Amsterdam)

      P2.71  Pathogenic variants in GPRC5B drive chronic brain oedema in MLC and identify GPRC5B as a therapeutic target
      Freya Kirwan (Amsterdam)

      P2.72  Looking at neurodevelopmental disorders through the lens of evolution: a role for the autolysosomal pathway
      Elly Lewerissa (Nijmegen)

      P2.73  Temporal processing in ADHD, autism, and their co-occurrence: a comparison with typically developing children
      Alina Munteanu (Rotterdam)

      P2.74  An iPSC-derived organoid model of hypoxic-ischemic brain injury  to test extracellular vesicle treatment
      Stela Papadaki (Utrecht)

      P2.75  Sleep-related neuronal network impairments associated with paroxysmal attacks in a mouse model of Alternating Hemiplegia of Childhood
      Chiara Rasconà (Leiden)

      P2.76  Decoding the RNF12 neural interactome: a FLAG IP-MS proteomics pipeline to identify TOKAS syndrome substrates
      Maurits Unkel (Rotterdam)

      P2.77  The effect of sleep quality on PPI, startle response and habituation in adults with autism compared to neurotypical adults
      Lois van der Wijck (Den Haag)

      P2.78  The effects of Tcf4 haploinsufficiency on play, sociability and communication in mice
      Francis van Rookhuizen (Amsterdam)

      P2.79  The effect of CHD2 haploinsufficiency on the autolysosomal function in hiPSC-derived astrocytes
      Patrycja Wypych (Nijmegen)

      P2.80  The effects of oral tributyrine supplementation in a double-hit depression model in mice
      Bibi Bek (Amsterdam)

      P2.81  The impact of maternal depression and antidepressant treatment on the maternal immune system
      Luna Does (Amsterdam)

      P2.82  The development of the Aggression Neuropsychological Assessment battery
      Zain Gangaram (Maastricht)

      P2.83  Escaping harm or earning reward: avoidance behavior in Sapap3-KO mice in an active avoidance task 
      Aikaterini Moysiadou (Amsterdam)

      P2.84  Impact of prenatal stress on the maternal (neuro)immune system
      Meike Mulder (Amsterdam)

      P2.85  A multi-angle approach to study synaptic E/I coordination in major depressive disorder
      Bas Ooijman (Nijmegen)

      P2.86  Does butyrate have therapeutic potential for treating depression? A preclinical intervention study
      Luca Rietveld (Amsterdam)

      P2.87  The role of the endocannabinoid system in stress-induced depression
      Lisette Siebert-ten Bolscher (Amsterdam)

      P2.88  Early-life stress in future mothers: hippocampal microglia during pregnancy
      Ines Vroegop (Amsterdam)

      P2.89  Establishing in vivo fiber photometry to investigate developmental aspects of elevated serotonin levels in somatosensory signal processing
      Nur Bodur (Nijmegen)

      P2.90  Mapping functional and anatomical organizations of somatosensory projections in the lateral cortex of the inferior colliculus
      Elena Compas (Rotterdam)

      P2.91  Dissecting the relationships between biophysical, morphological and electrophysiological properties of cortical dendrites
      Su Saka (Amsterdam)

      P2.92  Contribution of the primary visual cortex to compensatory eye movements function and development 
      Lisa-Maria Galca (Rotterdam)

      P2.93  Optogenetic manipulation of dorsolateral striatum medium spiny neuronal subpopulations during locomotion
      Meike Jongen (Amsterdam)

      P2.94  High-speed GEVI fiber photometry in mice to investigate mechanisms of deep brain stimulation in Parkinson’s disease
      Denis Torbin (Rotterdam)

      P2.95  Wave-like striatal dopamine peaks and troughs bracket spontaneous movement
      Nynke van Walraven (Amsterdam)

      P2.96  Investigating neurotoxicity in C. elegans during ageing: The role of quinolinic acid in mediating the protective effect of TDO-2 depletion
      Jules Borgers (Groningen)

      P2.97  Attractiveness of zebra finches songs: Calcium imaging and behavioral preference male song perception in a secondary auditory cortex-like brain region in female songbirds
      Linda De Pellegrin (Groningen)

      P2.98  Memory in motion: in vivo calcium imaging to investigate the neural substrate of tutor song memory in adult zebra finches
      Hidde Huisjes (Groningen)

      P2.99  Hepatic clocks and behavioural rhythmicity: is GPR146 the underlying factor driving food entrainment in mice?
      Indy Lopers (Groningen)

      P2.100  The hidden grammar of behaviour: a computational qpproach to reveal grooming microstructure
      Elizaveta Tatarnikova (Amsterdam)

      P2.101  Neural and behavioral mechanisms of approach–avoidance conflict
      Rafaela Gamboa von Groll (Amsterdam)

      P2.102  Hemispheric lateralization of DRD1-expressing medial amygdala projections in downstream pathways related to metabolic regulation
      Anastasia Marin (Amsterdam)

      P2.103  Early-life stress and later environmental modulations: impact on cortical plasticity and optimizing THC-vapor exposure in mice
      Roos van der Laan (Amsterdam)

      P2.104  Cocaine-induced conditioned place preference in serotonin transporter knockout rats is reduced by monoaminergic vesicle depletion
      Emanuela Vescan & Iwan van Oosterhout (Nijmegen)

      P2.105  What are we? Diving into how pairbonding shapes female zebra finch perception
      Andrés Viñas Martínez (Groningen)

      P2.106  GluA3-dependent regulation of parvalbumin-expressing interneurons and hippocampal memory dysfunction in Alzheimer’s disease
      Alisha Balhari (Amsterdam)

      P2.107  Linking representational drift to plasticity in biologically inspired continual learning
      Nikola Bátová (Groningen)

      P2.108  Optimizing activity-dependent labeling for locus coeruleus stress ensembles: a comparative study
      Weronika Gnat (Amsterdam)

      P2.109  A semi-naturalistic approach to charting rodent neuro-cognitive development and their interaction with the early life environment
      José Gomes Teixeira (Nijmegen)

      P2.110  Combining real and simulated neurons to evaluate predictive hippocampal representations
      Paula Gómez Méndez (Groningen)

      P2.111  The impact of ecologically relevant stimuli in assessing basic cognitive functions in rhesus macaques: implications for translational models
      Katarina Koch (Rijswijk)

      P2.112  Discriminating sex chromosome and gonadal hormone influences on hippocampal pattern separation with a touchscreen-based task
      Saga Lehtimäki (Groningen)

      P2.113  Structural brain effects of estrogen depletion in a mouse model of Alzheimer’s disease: a longitudinal deformation-based morphometry study
      Jacek Menżyński-Biskup (Groningen)

      P2.114  Structural changes following ovarian removal combined with circadian disturbances in a mouse model of AD
      Thijs Peters (Groningen)

      P2.115  Stochastic exploration of cortical microcircuit models for predictive processing
      Max Rensen (Nijmegen)

      P2.116  The impact of adolescent risk exposure on cognitive control and inhibition in Lister Hooded rats
      Linde van Dijken (Utrecht)

      P2.117  The role of theta oscillations in memory retrieval
      Livia Stein (Groningen)

      P2.118  Unmasking cell type-specific epigenetics through low-input nanopore sequencing
      Lisa Koole (Maastricht)

      P2.119  Optimising doxycycline treatment duration for maturation of rapidly induced iPSC-derived neurons
      Dimah Shaban (Amsterdam)

      P2.120  Computer vision-based framework for quantitative assessment of facial motor and speech function in awake brain surgery
      Cindy Steward (Rotterdam)

      P2.121  Using (high-density) micro-electrode array recordings to assess acute and developmental neurotoxicity in human iPSC-derived neuronal cultures after exposure to environmental contaminants
      Lennart van Melis (Utrecht)

      P2.122  The role of juvenile risky play in shaping decision-making in adult Lister Hooded rats
      Michelle Smolenaers (Utrecht)

    • Posters

      The two poster sessions are scheduled for Thursday, 25 June, at 17:15 and Friday, 26 June, at 16:45.

      If your abstract is selected for a poster presentation, when preparing your poster please remember that the maximum area available is 96 x 122 cm (width x height); the poster must have a portrait format. We recommend preparing your poster in a standard A0 size (841 x 1189 mm; width x height).

      "Portrait" is fine poster should be PORTRAIT    poster should NOT be LANDSCAPE "Landscape" not...

      Your poster should be readable from a 2-metre distance; as a rough guideline, use a font size of 72 pts for your title, and a minimum of 28 pts for your text.

      Posters must be mounted on the day of the presentation only, between 08:00 and the start of the first session of the day (10:00 on Thursday, and 09:00 on Friday).

      Posters must be removed at the end of the day only: 18:30 on Thursday and Friday. Posters from the Thursday session that are still up by Friday at 08:00 will be discarded by the venue personnel so that the Friday posters can be set up. Posters left behind after the conclusion of the meeting will be discarded by the venue personnel.