Dutch
Neuroscience Meeting
Dutch
Neuroscience Meeting
Dutch
Neuroscience Meeting
Tiel, The Netherlands • 25-26 June 2026
Tiel, The Netherlands
25-26 June 2026
Tiel, The Netherlands
25-26 June 2026
09:00 Registration (with Coffee & Tea)
10:00 Opening
10:10 Plenary Session
Session 1: Keynote Lecture
Chairs: Aleksandra Badura (Rotterdam) & Chun-Xia Yi (Amsterdam)
Margaret McCarthy (Baltimore, MD, USA) Power Play: How Steroids, Endocannabinoids and Behavior Sculpt Neural Development. (45')
11:10 Coffee & Tea
11:30 Parallel Sessions A
Session 2: Illuminating endocannabinoid action in neural circuits[Tuin & Waterkers]
Chairs: Daan van der Vliet (Rotterdam) & Tom van der Wel (Leiden)
István Katona (Bloomington, IN, USA) ImmunoSTORM and PharmacoSTORM super-resolution imaging of cannabinoid signaling in neurons and astrocytes (30')
Jeroen Punt (Leiden) Bioorthogonal probes to visualize endocannabinoids and their metabolism (20')
Corette Wierenga (Nijmegen) Endocannabinoids as mediators of local coordination of excitatory and inhibitory synapses
(20')
Sylvie Lesuis (Amsterdam) Stress-induced memory overgeneralization: The central role of endocannabinoid signaling (20')
Session 3: Building and leveraging large-scale single-cell censuses for neuroscience[Pink Lady]
Chairs: Vanessa Donega (Amsterdam) & Kimberly Siletti (Utrecht)
Rebecca Hodge (Seattle, WA, USA) Charting the cellular architecture of the human and non-human primate brain (30')
Christiaan de Kock (Amsterdam) Divergent Transcriptomic and Functional aging of Molecularly Defined Neuron Types in Human Brain (15')
Eileen Brouwer (Utrecht) Cellular underpinnings of eating disorders (15')
Bart Eggen (Groningen) The human CNS from a spatial perspective (15')
Aletta van den Bosch (Milan, Italy) Microglial states associate with lesion dynamics in multiple sclerosis (15')
Session 4: Glial regulation of neuronal activity and synaptic plasticity[Maaszaal]
Chairs: Nicky Scheefhals & Lot de Witte (Nijmegen)
Jimena Baleriola (Madrid, Spain) TBA (30')
Mark Verheijen (Amsterdam) Astrocyte-Synapse Structural Plasticity in Memory Function (15')
Bas Lendemeijer (Rotterdam) In vitro models to study human glial-neuronal interactions (15')
Carlos González Jimémez (Nijmegen) Microglial contributions to neural network dysfunction in Kleefstra Syndrome (15')
Nicky Scheefhals (Nijmegen) Better together: neuron-glia interactions shape synaptic maturation and plasticity in human iPSC-derived networks (15')
Session 5: Beyond neurotransmission: Serotonin's role in brain development across species[Bloesem]
Chairs: Judith Homberg & Sharon Kolk (Nijmegen)
Francesca Calabrese (Milan, Italy) Modulating the serotonergic system across generations: from mother to pup (30')
Marta Samine (Nijmegen) From neurodevelopment to behavior: impact of lifelong serotonergic dysregulation on prefrontal circuit maturation (15')
Hannah El Marroun (Rotterdam) Serotonin pathway-specific polygenic risk for psychiatric disorders and brain morphology in adolescents (15')
Judith Homberg (Nijmegen) Effect of maternal serotonergic genotype on offspring brain and behavioral development (15')
Jocelien Olivier (Groningen) The effects of cumulative early life stress on anxiety levels in male and female serotonin transporter knockout rats (15')
Session 6: Development and modulation of hippocampal circuits[Royal Gala]
Chairs: Suzanne van der Veldt (Groningen) & Freyja Ólafsdóttir (Nijmegen)
Andrew MacAskill (London, United Kingdom) Early life experience shapes hippocampal circuits for learning hidden rules (30')
Guido Meijer (Nijmegen) Same place, different context: dynamic switching between stimulus-outcome associations by the para-hippocampal network (15')
Guillaume Etter (Groningen) The preconfigured brain: How internal hippocampal sequences organize adult learning and memory (15')
Freyja Ólafsdóttir (Nijmegen) What can development tell us about the neuronal underpinnings of spatial memory? (15')
Suzanne van der Veldt (Groningen) Neuromodulatory tuning of hippocampal activity shapes defensive behavior (15')
Session 7: Multi-domain lifestyle approaches in the prevention and treatment of Alzheimer’s Disease: insights from preclinical and clinical studies[Wijnkers]
Chairs: Aniko Korosi & Emmy Hoeksema (Amsterdam)
Evgenia Salta (Amsterdam) Harnessing exercise to amend neuroinflammation in Alzheimer’s disease (30')
Lianne Remie (Nijmegen) The gut-immune-brain axis in cognitive aging: longitudinal evidence from a multidomain lifestyle intervention in older adults (15')
Yannick Vermeiren (Wageningen) Mediterranean-style diets and cognitive ageing: modulation of tryptophan metabolism in at-risk older adults (15')
Emmy Hoeksema (Amsterdam) Omega-3 interventions in Alzheimer’s Disease: where are we at? insights from clinical and preclinical studies (15')
Niek Renckens (Amsterdam) Microglia exhibit distinct morphological and phagocytic states depending on proximity to engram neurons and amyloid plaques (15')
13:00 Lunch
14:15 Parallel Sessions B
Session 8: Synaptic plasticity mechanisms in learning and memory[Maaszaal]
Chairs: Kubra Gulmez Karaca (Utrecht) & Janina Kupke (Amsterdam)
Alessio Attardo (Magdeburg, Germany) A new path towards the synaptic engram (30')
Kubra Gulmez Karaca (Utrecht) Time- and sex-dependent characterization of engram spine morphology in fear memory processing (15')
Renee Pullen (Amsterdam) From synapse structure to molecular identity: spatiomolecular mapping of mGluR5 in CA1 engram cell spines (15')
Robbert Havekes (Groningen) Reversing sleep loss-induced spatial and social amnesia (15')
Thije Willems (Amsterdam) GluA3 mediated synaptic mechanisms for memory consolidation during sleep (15')
Session 9: Voltage-gated ion channels in health and disease[Wijnkers]
Chairs: Marina Hommersom (Nijmegen) & Else Tolner (Leiden)
Massimo Mantegazza (Valbonne-Sophia Antipolis, France) Voltage‑gated sodium channels in neurological diseases: insights from genetic variants of NaV1.1/SCN1A (30')
Maarten Kole (Amsterdam) Beyond the node: voltage-gated channels and ion flow across the myelin landscape
(15')
Armagan Kocer (Enschede) Decoding Dysfunction: How Inherited Mutations Alter Kv4.3 Channel Gating and Lead to Spinocerebellar Ataxia 19/22 (15')
Marina Hommersom (Nijmegen) Human neuronal networks on micro-electrode arrays as a tool to assess genotype-phenotype correlation in CACNA1A-related disorders (15')
Else Tolner (Leiden) Linking channelopathy-related mutations to neurophysiological mechanisms in migraine and epilepsy (15')
Session 10: Individual differences in social behaviour and coping across species[Royal Gala]
Chairs: Rixt van der Veen (Amsterdam) & Michael van der Kooij (Utrecht)
Benjamin Jurek (Munich, Germany) Observing mice at home: Long-term deep phenotyping of social behavioral traits in a home-cage setting (30')
Jean-Christophe Billeter (Groningen) Modulation of sleep by social experience in Drosophila Melanogaster (15')
Lisa Bouwman (Amsterdam) Coping is of the essence: Using a complexity approach to integrate different coping behaviors after early life stress (15')
Bart Pollux (Wageningen) The role of the placenta in transferring maternal stress to developing embryos: a comparison of livebearing fish species with and without placenta (15')
Michael van der Kooij (Utrecht) Coping early in life: Automated tracking of parental mice gives new directions into the underpinnings of early life stress (15')
Session 11: Innovative iPS cell-derived neuronal models for translational therapy development[Bloesem]
Chairs: Katrin Linda (Nijmegen) & Femke de Vrij (Rotterdam)
Aleksandra Pękowska (Warsaw, Poland) Astrocytes and the evolution of neuronal developmental tempo (30')
Carles Calatayud Aristoy (Leuven, Belgium) Electrophysiological mapping of human striatal microcircuits enables Parkinson's disease stratification (15')
Katrin Linda (Nijmegen) Advancing therapeutic insight with human iPS cell-derived neuron–astrocyte models (15')
Dana Vervloet (Rotterdam) Exploring the potential of antisense oligonucleotide therapy for a RASopathy using iPSC-based models. (15')
Juliette Kamp (Rotterdam) Investigating the therapeutic potential of SYNGAP1 splice-switching oligonucleotides (15')
Session 12: Metabolic and environmental stressors at the roots of dementia[Tuin & Waterkers]
Chairs: Sébastien Foulquier (Maastricht) & Martina Schmidt (Groningen)
Emma Kasteel (Utrecht) Plastic not-so-fantastic? Neurotoxic effects of micro- and nanoplastics in vitro (30')
Kenneth Vanbrabant (Hasselt, Belgium) Early-life air pollution exposure as a driver of later-life cognitive vulnerability (15')
Martina Schmidt (Groningen) Environmental stressors in experimental Alzheimer models (15')
Amanda Kiliaan (Nijmegen) Obesity and brain health (15')
Sébastien Foulquier (Maastricht) Cardiometabolic stressors as drivers of vascular cognitive impairment (15')
Session 13: New crucial roles of neuroglial populations: insight from the glioma-induced changes[Pink Lady]
Chairs: Lucas Baudouin (Amsterdam) & Marina Trombetta Lima (Groningen)
David Ohayon (Toulouse, France) Astrocyte heterogeneity and glioblastoma microenvironment (30')
Alexandra de Reus (Utrecht) The cellular landscape of the glioblastoma invasive front: uncovering mechanisms driving glioblastoma invasion in the tumor micro-environment (15')
Marina Trombetta Lima (Groningen) Reprogramming the tumor microenvironment through Matrix Metalloproteinase Inhibitors (15')
Frank Kruyt (Groningen) Identification of novel mechanisms regulating microtube-based cellular connectivity and tumor aggressiveness in glioblastoma (15')
Lucas Baudouin (Amsterdam) Multiscale analysis of cognitive impairment in IDH-mutant glioma: from connectome to oligodendrocyte dynamics (15')
15:45 Coffee & Tea
16:15 Plenary Session
Session 14: Keynote Lecture
Chair: Vanessa Donega (Amsterdam)
Candida Snow (Zwolle) Take off your culture glasses (45')
17:15 Posters & drinks
Session 15: Poster session 1
18:30 Dinner
20:00 Plenary Session 21:00 Social
Session 16: Award CeremonyKeynote Lecture
Illuminating endocannabinoid action in neural circuits
Building and leveraging large-scale single-cell censuses for neuroscience
Glial regulation of neuronal activity and synaptic plasticity
Beyond neurotransmission: Serotonin's role in brain development across species
Development and modulation of hippocampal circuits
Multi-domain lifestyle approaches in the prevention and treatment of Alzheimer’s Disease: insights from preclinical and clinical studies
Synaptic plasticity mechanisms in learning and memory
Voltage-gated ion channels in health and disease
Individual differences in social behaviour and coping across species
Innovative iPS cell-derived neuronal models for translational therapy development
Metabolic and environmental stressors at the roots of dementia
New crucial roles of neuroglial populations: insight from the glioma-induced changes
Keynote Lecture
Poster session 1
Award Ceremony
08:30 Registration (with Coffee & Tea)
09:00 Parallel Sessions C
Session 17: How positive and negative early life events shape food intake and related behaviors[Royal Gala]
Chairs: Frank Meye & Gisela Lazzarino (Utrecht)
Mark Rossi (New Brunswick, NJ, USA) Rewiring of hypothalamic feeding circuits by early-life overnutrition (30')
Hanneke van Santen (Utrecht) Acquired hypothalamic dysfunction and its metabolic consequences (20')
Natalia Schilder (Amsterdam) The effects of oral tributyrin supplementation in a murine, double-hit model of depression (20')
Gisela Lazzarino (Utrecht) How early-life risky play opportunities influence prefrontal cortical circuits and inhibitory control over food reward seeking (20')
Session 18: Patterns of divergence: Sex effects during brain development from cells to circuits[Bloesem]
Chairs: Aleksandra Badura (Rotterdam) & Sam de Kater (Nijmegen)
Gabriele Rune (Berlin, Germany) Sex-specific regulation of neurosteroid synthesis by GnRH and its relevance for synaptic plasticity in the hippocampus (30')
Joram Mul (Amsterdam) Sex-dependent neurobiology of exercise training-induced stress resilience: a focus on ∆FOSB (15')
Anna Sancho Balsells (Amsterdam) Sex-specific effects of prenatal stress on fetal microglia (15')
Stephanie Dijkhuizen (Rotterdam) Sensory processing and cognitive impairments in people with SHANK2 loss of function mutations and in the SHANK2 haploinsufficient mutant mice (15')
Sam de Kater (Nijmegen) Intrinsic properties of CA1 pyramidal cells are set by sex hormones in organotypic hippocampal slices from male and female mice (15')
Session 19: Mitochondrial power failure: at the crossroad of environmental exposure and genetic susceptibility in brain pathologies[Tuin & Waterkers]
Chairs: Amalia Dolga & Tingting Chen (Groningen)
Janine Santos (Durham, NC, USA) From screens to systems: discovering new roles for mitochondria in human health (30')
Tingting Chen (Groningen) PSEN1 ΔE9 NPC-Derived Extracellular Vesicles Induce Neural and Metabolic Impairments in Brain Organoids (15')
Vedrana Stefanic (Nijmegen) Abnormal synaptic transmission in mouse brain and human neuronal cell models of mitochondrial disease (15')
Teresa Mitchell-Garcia (Groningen) Exposure to diesel exhaust particles impairs the function of human iPSC-derived microglia with the LRRK2 G2019S mutation (15')
Angelica Sabogal Guaqueta (Amsterdam) Mitochondrial dysfunction as a mediator of heavy metal neurotoxicity in microglia. (15')
Session 20: How omics studies can tell tales about the AD and FTD brain[Wijnkers]
Chairs: Sabine Spijker & Roberta Giannelli (Amsterdam)
Ehsan Pishva (Maastricht) Large-scale multiomics investigation of cortical miRNA changes in Alzheimer's Disease (30')
Roberta Giannelli (Amsterdam) Multi-omics approach for defining the disease trajectory of FrontoTemporal Dementia (15')
Guus Smit (Amsterdam) The proteomic profile of Von Economo neurons (15')
Betty Tijms (Amsterdam) Alzheimer's disease pathophysiological subtypes based on CSF proteomics have distinct CSF lipidomics profiles (15')
Lynn van Olst (Groningen) Alzheimer brain transcriptomics (15')
Session 21: Spike fast, die young? Development, maturation, plasticity, dysfunction and decline of Parvalbumin-positive neurons and their Perineuronal Nets[Maaszaal]
Chairs: Moritz Negwer & Corette Wierenga (Nijmegen)
Monika Moissidis (London, United Kingdom) A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons (15')
Moritz Negwer (Nijmegen) Whole-brain, three-dimensional visualization of parvalbumin neurons and perineuronal nets (15')
Martijn Selten (London, United Kingdom) Mechanisms of homeostatic regulation in PV interneurons (15')
Ronald van Kesteren (Amsterdam) Selective interneuron vulnerability in a mouse model of Alzheimer’s disease (15')
Laure Verret (Toulouse, France) The role of hippocampal parvalbumin neurons in memory deficits and functional recovery in Alzheimer’s models (30')
Session 22: Antisense oligonucleotide therapeutics for brain disorders[Pink Lady]
Chairs: Ronald Buijsen (Leiden) & Dana Vervloet (Rotterdam)
Ype Elgersma (Rotterdam) Developing Antisense Oligonucleotide (ASO) therapy for Neuordevelopmental Disorders: From proof of concept to clinical trials (30')
Ronald Buijsen (Leiden) How to synthesize ASOs? (15')
Gijs-Jan Scholten (Leiden) Allele-specific antisense oligonucleotides to treat Spinocerebellar Ataxia Type 1 (SCA1) (15')
Inge Zuhorn (Groningen) Cellular processing of delivery vehicles (15')
Marjon Pasmooij (Utrecht) Regulatory aspects of ASO therapeutics (15')
10:30 Coffee & Tea
11:00 Parallel Sessions D
Session 23: Synaptic and network alterations in early Alzheimer's disease[Tuin & Waterkers]
Chairs: Lucas Lumeij & Ronald van Kesteren (Amsterdam)
Stefan Remy (Magdeburg, Germany) Synaptic and network dysfunction in Alzheimer's disease (30')
Zehra Kazmi (Amsterdam / Nijmegen) Excitatory targets, inhibitory consequences: How amyloid-β oligomers tip the scales of network E/I balance during early Alzheimer’s disease (15')
Lucas Lumeij (Amsterdam) The role of AMPA receptor subunit GluA3 in amyloid-β-induced synaptic and network alterations in Alzheimer's disease (15')
Kevin Marinus (Amsterdam) Alzheimer-causing PSEN1 mutations interfere with early neuronal differentiation in a human iPSC-derived model for neurodevelopment (15')
Anne van Nifterick (Amsterdam) Unravelling hyperexcitability in Alzheimer's disease: towards non-invasive network markers (15')
Session 24: Intrinsic plasticity: shaping signals from input through output to circuits[Bloesem]
Chairs: Ting-Feng Lin (Utrecht) & Maarten Kole (Amsterdam)
Guillaume Drion (Liège, Belgium) Cellular homeostasis and neuromodulation as core mechanisms of intrinsic plasticity and network function. (30')
Zahra Hemmat (Rotterdam) Cerebellar subpopulation-specific differences in intrinsic excitability and plasticity related to distinct movement kinematics (15')
Roberto D’Angelo (Utrecht) Social Stress and Dopamine Oppositely regulate Intrinsic Plasticity of Prefrontal Cortical Outputs to the Nucleus Accumbens and Basolateral Amygdala in the Regulation of Palatable Food Intake
(15')
Vasiliki Theodorou (Amsterdam) Chronic network silencing triggers distinct AIS plasticity in excitatory and inhibitory neurons (15')
Ting-Feng Lin (Utrecht) Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum (15')
Session 25: Human in vitro and primary tissue models of brain development and disease[Maaszaal]
Chairs: Steven Sloan (Amsterdam) & Noelia Anton Bolanos (Utrecht)
Debby Silver (Durham, NC, USA) Building our brains: from development to evolution (30')
Noelia Anton Bolanos (Utrecht) Mirroring human Brain Development and Disease using Brain Organoids as Avatars (15')
Femke de Vrij (Rotterdam) Disease modeling using human adherent cortical organoids (15')
Anna Pagliaro (Utrecht) Deciphering mechanisms driving human brain development and expansion: insights from novel in vitro organoid systems (15')
Evgenia Salta (Amsterdam) Single-cell molecular mapping of human adult hippocampal neurogenesis in Alzheimer’s disease and resilience
(15')
Session 26: Neuromorphic computing[Wijnkers]
Chairs: Arezoo Alizadeh (Nijmegen) & Mario Negrello (Rotterdam)
Herbert Jaeger (Groningen) A semantic theory of universal computation - why? therefore! (30')
Chiara De Luca (Zurich, Switzerland) Neuromorphic digital twins for closed-loop neurostimulation (20')
Tim Kamsma (Utrecht) Brain-inspired computing in a brain-inspired medium (20')
Arezoo Alizadeh (Nijmegen) Space-By-Time Semi-NMF: A Decomposition Approach for Single-Trial Neural Decoding (20')
Session 27: Expanding dimensions of cAMP signaling: from spatial nanodomains to cell-wide integration[Pink Lady]
Chairs: Melissa Schepers (Diepenbeek, Belgium) & Tim Vanmierlo (Maastricht / Hasselt, Belgium)
Cécile Derieux (Mainz, Germany) cAMP nanodomains and GPCR signaling (30')
Rosa Randoe (Amsterdam) GPCR signaling at astrocyte endfeet: GPRC5B and the biology of brain edema (15')
Martina Schmidt (Groningen) The Role of cAMP in Neurodegenerative Models (Eng) (15')
Rob Leurs (Amsterdam) Modulation of GPCR-based cAMP signalling with light (15')
Tim Vanmierlo (Maastricht / Hasselt, Belgium) cAMP Signaling as Hub and Driver in (re)Myelination (15')
Session 28: Adaptive forgetting mechanisms: translational approaches across neuroscience disciplines[Royal Gala]
Chairs: Conny Quaedflieg (Maastricht) & Kevin van Schie (Tilburg)
Michael Anderson (Cambridge, United Kingdom) Improving mental health by training the mechanisms of adaptive forgetting (30')
Martyna Gwiazda (Maastricht) Intentional suppression of memories consolidated under stress (20')
Ralph Wientjens (Amsterdam) Memory suppression versus Extinction: disentangling effects on memory content and emotional affect (20')
Kevin van Schie (Tilburg) Non-invasive brain stimulation to enhance individuals’ capacity to control intrusive memories (20')
12:30 Lunch
13:45 Plenary Session
Session 29: Keynote Lecture
Chair: Conny Quaedflieg (Maastricht)
Michael Anderson (Cambridge, United Kingdom) Adaptive forgetting for mental health (45')
14:45 Coffee & Tea
15:15 Parallel Sessions E
Session 30: Rebalancing neuroscience: revealing sex-dependent mechanisms in health and disease[Maaszaal]
Chairs: Sabine Spijker & Sophie van der Sluis (Amsterdam)
Sofie Valk (Düsseldorf, Germany) Spatiotemporal axes of brain organisation to understand health and disease (30')
Anne Marije Kaag (Amsterdam) The influence of ovarian hormones on the neural mechanisms underlying addiction (15')
Cato Romero (Amsterdam) Sex differences in genetic pathways underlying ischaemic heart disease–depression comorbidity (15')
Lin Zhang (Amsterdam) Sex differences in the cholinergic system in depression and suicide (15')
Sabine Spijker (Amsterdam) Diversity in depression-induced proteomic signatures (15')
Session 31: Dynamics of blood vessels in the maturing brain: mechanisms of formation, repair and communication with neurons[Wijnkers]
Chairs: Carla Gomes da Silva (Utrecht) & Amparo Acker Palmer (Frankfurt, Germany)
Amparo Acker Palmer (Frankfurt, Germany) Angioneurins orchestrate neurovascular development and circuit formation (30')
Carlos Flores Clara (Utrecht) New mechanisms of glia-mediated vascular repair during brain development (20')
Henrique Nogueira Pinto (Amsterdam) From stem cells to neurovascular networks: Building a functional human blood-brain barrier in vitro (20')
Tommaso Ristori (Eindhoven) Integrating experiments with simulations to unravel pathological angiogenesis (20')
Session 32: Shared and distinct mechanisms in synucleopathies and tauopathies: synergistic to solutions (hosted by Alzheimer Nederland and ParkinsonNederland)[Pink Lady]
Chairs: Wiep Scheper & Wilma van de Berg (Amsterdam)
Wiep Scheper (Amsterdam) Neuronal resilience to tau and α-synuclein pathology: shared mechanisms and opportunities (15')
Marcel Verbeek (Nijmegen) What body fluid biomarkers can tell learn us about overlap and differences in neurodegenerative disorders (15')
Wilma van de Berg (Amsterdam) Neuropathological evidence of co-pathologies in synucleinopathies (15')
Bart Eggen (Groningen) Microglia heterogeneity across neurodegenerative disorders (15')
Panel discussion with the speakers incl. questions from the audience (30')
Session 33: Modeling iPSC-Microglia: insights & communication (MIMIC-NL)[Royal Gala]
Chairs: Lot de Witte (Nijmegen) & Amalia Dolga (Groningen)
Šárka Lehtonen (Kuopio, Finland) Multiscale Modeling of Human Microglia in Synucleinopathies: From Cellular States to Organoid and In Vivo Neurodegeneration (30')
Lot de Witte (Nijmegen) Advancing insights into microglial responses to neuronal hyperexcitability using iPSC models (15')
Renata Baptista Vieira de Sa (Amsterdam) Microglia cause HIV-induced transcriptional and metabolic changes in human neural organoids (15')
Kim Kleijn (Amsterdam) iPSC-derived microglial interferon states in drug screening for Alzheimer’s disease (15')
Amalia Dolga (Groningen) Human iPSC-derived microglia change the cellular metabolic profile of the brain organoids (15')
Session 34: The Locus Coeruleus across states: noradrenergic modulation from synapses to behavior[Bloesem]
Chairs: Danai Riga & Helmut Kessels (Amsterdam)
Jordan McCall (St. Louis, MO, USA) Parsing pain and aversion in the locus coeruleus noradrenergic system (30')
Helmut Kessels (Amsterdam) Effects of noradrenaline signaling on synaptic plasticity (15')
Danai Riga (Amsterdam) Deciphering the neural footprints of physical and emotional adversity (15')
Alejandro Osorio-Forero (Amsterdam) The locus coeruleus across vigilance (15')
Lukas van Herk (Utrecht) Pharmacologically induced stress affects moral decision-making, working memory, and risk-taking in military personnel (15')
Session 35: Integrative computational neuroscience: from deep learning to spikeing and data-driven approaches[Tuin & Waterkers]
Chairs: Ellen Boven & Zhenyu Gao (Rotterdam)
Loreen Hertäg (Berlin, Germany) Modelling prediction errors: from neurons to circuits to cortical layers (30')
Jorge Mejías (Amsterdam) Biological architectures for predictive coding (15')
Heike Stein (Paris, France) Reconstructing the dynamics of locomotion explains the emergence of coordinated gaits on structured surfaces in mice (15')
Fleur Zeldenrust (Nijmegen) Heterogeneity in the brain: lessons from theory and experiment
(15')
Pedro Gonçalves (Leuven, Belgium) Machine learning for mechanistic insight in neuroscience (15')
16:45 Posters & drinks
Session 36: Poster session 2
18:00 Closure DNM 26 & poster prizes
Thursday .::. 25 June, 17:15
P1.1 The translation-dependent neuronal ER proximity proteome reveals novel candidate proteins regulating subcellular translation in neurons
Vivienne Aline Bauer (Leiden)
P1.2 Zebrafish Fignl1 regulates the Slit/Robo pathway, required for retinal axon guidance
Naomi Berbée (Amsterdam)
P1.3 From mouse models to human blood: early‑life stress‑induced mitochondrial dysfunction as a translational marker of Alzheimer’s disease
Anne Bissay (Amsterdam)
P1.4 Roles of ER–Golgi contact sites on polarized protein trafficking in neurons
Dilixiati Dilikaibier (Utrecht)
P1.5 Beyond bradychrony: species-divergent dendritic maturation and synaptic function in great ape iNeurons
Max Sterling (Nijmegen)
P1.6 Establishing an organotypic hippocampal slice model to study astrocyte–synapse interactions
Imane Al Idrissi (Almere)
P1.7 Effect of sleep deprivation on hippocampal synaptic plasticity: a SABV approach
Elena Ascension Horcas (Groningen)
P1.8 Region and age-related microglia heterogeneity in the healthy human brain
Anouck Bahnerth (Amsterdam)
P1.9 Investigating the role of SHANK in mPFC engram cells on synaptic connectivity and memory retrieval
Indy Batteram (Amsterdam)
P1.10 The intracellular molecular mechanisms underlying GluA3-containing AMPA-receptor plasticity
Iris Berden (Amsterdam)
P1.11 Association between dendritic morphology and subthreshold signal propagation in mouse and human cortical layer 2 & 3 pyramidal neurons
Nicolás Beyer Diaz-Guardamino (Amsterdam)
P1.12 Expanding the tripartite synapse
Thomas Blok (Amsterdam)
P1.13 Assessing neuronal plasticity in the mPFC after cannabis exposure using ImageJ
Aileen Blom (Utrecht)
P1.14 Grasping the structural astrocyte-synapse interaction in early Alzheimer’s disease with AstroGRASP
Cristina Boers Escuder (Amsterdam)
P1.15 EPSP propagation speed in human cortical neurons
Tom Coopmans (Amsterdam)
P1.16 Keep the balance: chronic silencing triggers different AIS adaptations in excitatory and inhibitory neurons
Ana Rita da Cunha (Amsterdam)
P1.17 From SNAREs to signals: deciphering the exocytic machinery controlling ion channels at the axon initial segment
Lukas de Haas (Amsterdam)
P1.18 Neurobiological consequences of chronic sleep loss: hippocampal neuronal plasticity and BDNF-signaling
Nienke de Vries (Groningen)
P1.19 Microglial regulation of memory engram stability in Alzheimer’s Disease: spatial and activity-dependent mechanisms
Evie de Wijs (Amsterdam)
P1.20 The local role of cell death proteins in inhibitory synapse elimination
Troy Kapteijns (Nijmegen)
P1.21 Effects of Camk2a and Camk2b double knockout on neuronal excitability in hippocampal neurons
Nadine Maas (Rotterdam)
P1.22 Species-specific astrocytic specialization and glutamate clearance kinetics in human and mouse neocortex
Bianca Marin (Amsterdam)
P1.23 Interplay between axon initial segment geometry and somatodendritic characteristics shape action potential initiation in human layer 2/3 pyramidal neurons
Hanna Marteijn (Amsterdam)
P1.24 High-resolution spatiomolecular mapping of CA1 engram cell synapses
Renee Pullen (Amsterdam)
P1.25 Subtype-specific regulation of metabotropic glutamate receptor surface mobility links spatial organization to receptor function
Dimitrios Samouil (Amsterdam)
P1.26 Nanoscale organisation and mobility of metabotropic glutamate receptors
Archit Singh (Amsterdam)
P1.27 Beyond protein abundance: synaptic phosphoproteomic signatures of contextual fear memory
Kim Verdaasdonk (Amsterdam)
P1.28 Noelin as a molecular regulator of synapse-specific AMPA receptor organization
Rozanne Voorvelt (Amsterdam)
P1.29 Effects of developmental and epileptic encephalopathy-associated gene, AP2M1, on synaptic transmission in human iPSC-derived neurons
Varvara-Maryia Zlotnik (Amsterdam)
P1.30 Investigating EV-miRNA-regulated inflammatory and stress pathways in SARS-CoV-2–associated neurodegeneration
Gunjan Bawne (Rijswijk)
P1.31 From neuroinflammation to neuroprotection: TNFR2 agonist treatment in a mouse model of Alzheimer’s disease
Irem Bayraktaroglu (Groningen)
P1.32 Investigating the efficacy of a novel TNFR2 agonist in male AD mice
Ruben Blaak (Groningen)
P1.33 The effects of early handling and sex on Alzheimer’s disease-related pathologies in 6-month-old APP/PS1 mice
Alise Bobkova (Amsterdam)
P1.34 Exploring the neuroprotective role of extracellular vesicles against ferroptosis-mediated neurodegeneration
Daria Costache (Groningen)
P1.35 The effect of progranulin loss on neuronal secretory autophagy
Fleur de Jager (Utrecht)
P1.36 Visual evoked potentials enable longitudinal monitoring of remyelination in chronic EAE
Zoë Donders (Maastricht)
P1.37 The effect of presenilin loss on neuronal secretory autophagy
Arana Erken (Utrecht)
P1.38 Unraveling the role of C9ORF72 using iNeurons
Larissa Goes (Utrecht)
P1.39 Using patient-derived PSEN1-mutant iPSCs to model excitation/inhibition imbalance in Alzheimer’s disease
Tasha Ibrahim (Amsterdam)
P1.40 Characterization of hippocampal pathology in a leptomeningeal inflammation model of Multiple Sclerosis
Ilina Ilieva (Amsterdam)
P1.41 Assessing neuroinflammation and repair after TNFR2 agonist treatment in aged multiple sclerosis
Alie-Yke Jonkman (Groningen)
P1.42 Exploring the effect of a novel TNFR2 agonist on motor functions and mechanical allodynia in an aging MS model
Mariëlle Kuipers (Groningen)
P1.43 Is it ever too early to start to worry? Investigating the effects of early life stress combined with social stress later in life on neuroinflammation and Alzheimer’s disease
Giulia Mozzanica (Groningen)
P1.44 Selective TNF receptor 2 activation alleviates inflammation and neurological deficits in Multiple Sclerosis
Natalia Ortí Casañ (Groningen)
P1.45 Microglia exhibit distinct morphological and phagocytic states depending on proximity to engram neurons and amyloid plaques
Niek Renckens (Amsterdam)
P1.46 Interactive effects of artificial light at night and 3xTg-AD genotype on circadian rhythmicity and Alzheimer’s disease markers
Anuja Rui (Groningen)
P1.47 Investigating the link between SARS-CoV-2 and Parkinson’s Disease using
patient-derived midbrain organoids
Matilde Ruo (Amsterdam)
P1.48 Capturing the neurovascular-immune interface in Alzheimer’s disease
Sofie Schuringa (Groningen)
P1.49 Piecing Cornelia de Lange syndrome together: one mosaic brain organoid at a time
Marieke Alzeer (Rotterdam)
P1.50 Tg-mediated roles in sleep/memory, & different monoamine transporters
Carolina Antunes Pereira (Nijmegen)
P1.51 Deciphering blood-brain barrier contributions to sleep disturbances in autism spectrum disorder
Theodóra Ægisdóttir (Nijmegen)
P1.52 The neurodevelopmental disorder-associated CAMK2A-Thr286Pro variant leads to severe molecular, behavior, and synaptic plasticity deficits in mice
Jaime Borregon Jimenez (Rotterdam)
P1.53 Peroxisomes: the forgotten organelle
Juliette Chevalier (Amsterdam)
P1.54 FoxP regulates systemic metabolic rate and sleep stability via repression of the mitochondrial enzyme Pepck2 in Drosophila
Melanie de Wit (Nijmegen)
P1.55 Monoaminergic regulation of sleep and memory in Drosophila melanogaster
Madilyn Ghai (Nijmegen)
P1.56 Roles of monoamine transporters and receptors in sleep/memory using Drosophila melanogaster
Eline Hamersma (Nijmegen)
P1.57 Two genotypes, one brain: modeling mosaic Cornelia de Lange Syndrome using patient-derived cortical brain organoids
Amber Hof (Rotterdam)
P1.58 Advancing neurodevelopmental disorder therapy through mechanistic insights of antisense oligonucleotide
Qianjun Ma (Rotterdam)
P1.59 Axiomer™ mediated RNA editing of premature termination codon results in functional correction in MECP2 for Rett syndrome
Marko Potman (Leiden)
P1.60 ERASOR: a platform to design and select antisense oligonucleotides for personalized treatment of neurodevelopmental disorders
Thierry Roob (Rotterdam)
P1.61 Molecular mechanisms underlying RHOBTB2-related neurodevelopmental disorders and exploring its therapeutic potential
Salma Sennouni (Rotterdam)
P1.62 Defining RNF12 function in the X-linked neurodevelopmental disorder Tonne-Kalscheuer syndrome
Kyra Swildens (Rotterdam)
P1.63 Designing a broadly applicable ASO therapy for SYNGAP1 disorders
Jip van den Hooff (Rotterdam)
P1.64 UBE3A-neighbouring genes on chromosome 15q contribute to Angelman syndrome phenotype
Amy van Hattem (Rotterdam)
P1.65 Modelling CDKL5 deficiency disorder in a human in vitro neuronal model
Xiuming Yuan (London, United Kingdom)
P1.66 Finding the sweet spot: a comparative evaluation of antibiotic regimens for microbiome depletion in rats prior to FMT
Maria Aydin (Nijmegen)
P1.67 Effects of mindfulness training on self-referential processing in help-seeking youth with internalizing symptoms: behavioural and neural evidence from the PRYME trial
Judith Bläsing (Nijmegen)
P1.68 Neurobiology of mitochondria, miRNA-132 and perineuronal nets in the human nucleus basalis of Meynert in relation to depression and suicide
Eleni Bovali (Amsterdam)
P1.69 Chronic restraint stress and whole-body metabolism: insights from ventral hippocampus and hypothalamus
Paola Brivio (Milan, Italy)
P1.70 Hypothalamic ensembles driving maladaptive behaviour in the activity-based anorexia model
Eileen Brouwer (Utrecht)
P1.71 Effects of time-of-day dependent esketamine administration on circadian
rhythmicity in wistar-kyoto rats
Simone Cidoni (Groningen)
P1.72 A proteomics approach to CNV mouse models in understanding affected molecular and cellular pathways in schizophrenia
Suchita Reddy Enugala (Amsterdam)
P1.73 Gender differences in alcohol-cue reactivity: the role of childhood trauma
Alexandru-Constantin Hanches (Amsterdam)
P1.74 Minocycline disrupts cocaine- but not predator odour-related memory reconsolidation: sex-specific behavioural responses to predatory threat
Lara Loermans (Nijmegen)
P1.75 Mapping neuronal ensembles during binge eating in the ventral tegmental area in an anorexia nervosa-like context
Demi Pastoor (Utrecht)
P1.76 Characterizing ventral tegmental area neuronal ensembles in stress-induced binge eating
Anne van Oosterhout (Utrecht)
P1.77 Guts2Beat depression: microbial metabolites from patients with depression to counteract cellular stress in microglia-containing cortical organoids
Rivka Vollebregt (Amsterdam)
P1.78 Time-of-day dependant effects of esketamine on circadian rhitmicity in a rat model of depression
Jasper Wannet (Groningen)
P1.79 From microbes to mood: piloting a human-to-rat FMT model to explore gut–brain molecular pathways and behavioral phenotypes
Lotte Wekking (Nijmegen)
P1.80 2P-imaging of inhibitory interneurons response patterns to electrical microstimulation for cortical visual restoration
Isabella Andersen (Amsterdam)
P1.81 Neuromodulation of inhibitory bouton formation via PKA
Ségolène Bompierre (Nijmegen)
P1.82 Non-polio enterovirus A71 and D68 infection of human neuromuscular organoids reveals distinct mechanisms of neuromuscular impairment
Renata Baptista Vieira de Sa (Amsterdam)
P1.83 Love at first hearing? Tracking female zebra finch representations of the male's song through pair-bonding using calcium imaging
Ilse Bakker (Groningen)
P1.84 Wired for company: gating of social experience by the circadian clock in Drosophila melanogaster females
Vasileios Kapantaidakis (Groningen)
P1.85 Whole-brain gene expression and neuronal activity at cellular resolution in behaving zebrafish
Emmanuel Marquez Legorreta (Utrecht)
P1.86 Decoding sleep and wakefulness from chronically implanted intracortical signals in a communication brain-computer interface user
Elena Offenberg (Utrecht)
P1.87 Genetic basis of natural variation in sociability
Fiete Schritt (Groningen)
P1.88 Human-specialised subthreshold resonance in cortical interneurons driven by subthreshold currents
Sarah Scott (Amsterdam)
P1.89 Activation of D2-expressing medium spiny neurons in the nucleus accumbens core mirrors the delaying effect of novelty exposure on feeding onset in rats
Astrid van Irsen (Amsterdam)
P1.90 A neural symphony: DRD1 neurons in the central clock orchestrate sleep and autonomic balance in rats
Vanessa Veronica (Amsterdam)
P1.91 The effects of glucocorticoids on remote memory and engram formation
Tamara Versluis (Amsterdam)
P1.92 Joint dopamine and serotonin dynamics in adaptive learning
Beatriz de Carvalho (Amsterdam)
P1.93 CADM2 overexpression in the medial prefrontal cortex of female mice: effects on alcohol self-administration and cue-induced relapse
Irene Dolfini (Amsterdam)
P1.94 Chemogenetic activation of medial amygdala dopamine receptor D1+ neurons transiently improves glucose response
Roberta Tandari (Amsterdam)
P1.95 The role of GluA3 on network synchrony and memory consolidation
Zerra Blok (Amsterdam)
P1.96 Mindfulness-based intervention and the relationship between Internalizing symptoms and Pavlovian-to-instrumental transfer in youth
Myrthe Brouwer (Nijmegen)
P1.97 Patterns of decline: sex differences in the onset of cognitive deficit in TgF344 rat model of Alzheimer’s disease
Julia Burgos Flores (Groningen)
P1.98 The impact of early-life cannabis exposure on social play behaviour and cognitive control in rats
Sem Harder (Utrecht)
P1.99 Mapping emotional stress: differential spatio-temporal encoding within key nodes of the stress-coping network
Tudor Ianovici (Amsterdam)
P1.100 Dissociating gonadal and chromosomal sex effects on memory after circadian disturbance
Amber Kal (Groningen)
P1.101 Cumulative stress and cognitive ageing: insights from population cohorts and a translational framework
Jiahao Li (Groningen)
P1.102 Spatial memories unlocked – reversing sleep deprivation-induced amnesia in female mice
Suzanne Lunshof (Groningen)
P1.103 Do I know you? Retrieving sleep deprivation-induced amnesia in social memory in female mice
Giorgia Marrone (Groningen)
P1.104 Supplementation of seaweed extracts to the diet reduces symptoms of Alzheimer’s Disease in the APPswePS1ΔE9 mouse model
Nikita Martens (Rotterdam)
P1.105 Temporal dynamics of Atf3 expression in learning and memory
Sandra Parisi (Amsterdam)
P1.106 Memory under stress: dissecting the role of engram cells and glucocorticoids in memory generalization
Arianna Riera-Llobet (Amsterdam)
P1.107 An SABV and translational perspective on the consequences of poor sleep on hippocampal function
Li-Yan Sijbolts (Groningen)
P1.108 Is it you my friend? Effects of sleep deprivation on memory engram encoding multiple social experience
Caterina Stacchiola (Groningen)
P1.109 Structural plasticity of fear memory engram across time and sex
Noor van den Heuvel (Utrecht)
P1.110 Observational learning of prey capture learning in a rat model of autism
Lucas Wahl (Waltham, MA, USA)
P1.111 Expression of the immediate early gene ATF3 in memory-related limbic regions following contextual fear conditioning
Fiona Woolf Moñino (Amsterdam)
P1.112 Looking beyond the diffraction limit: developing single-molecule microscopy approaches to resolve nanoscale structures in brain tissue
Giulia Anderson (Amsterdam)
P1.113 VoltZilla: an integrated software for real-time voltage imaging and feedback control
Hunor Bartalis-Szélyes (Rotterdam)
P1.114 Optimizing spatiomolecular mapping of synaptic subpopulations
Arend Breukelaar (Utrecht)
P1.115 Lab on a breadboard: a fully automated setup for hands-free longitudinal calcium imaging recordings
Massimiliano Coscia (Groningen)
P1.116 Benchmarking organoid dissociation strategies for single-nucleus transcriptomics profiling
Emily Farrugia (Groningen)
P1.117 Detection of subcompartment-specific proteomes in astrocytes
Anna Gradl (Amsterdam)
P1.118 Developing acute and robust re-localization tools to unravel the function of ER cisternae in dendrites
Daphne Jager (Utrecht)
P1.119 A versatile miniature two-photon microscope enabling multicolor deep-brain imaging
Richard Kozma (Nanjing, China)
P1.120 An affordable smoke delivery system for the inhaled administration of combusted or vaporized cannabis to rodents
Thijs Messing (Utrecht)
P1.121 SINEUP-mediated enhancement of Kv7.2 translation: development and in vitro validation
Inez van Wijk (Amsterdam)
P1.122 An analysis pipeline for single molecule imaging of endogenous synaptic proteins in brain tissue
Bram Willems (Amsterdam)
Friday .::. 26 June, 16:45
P2.1 Expansion microscopy reveals vascular damage sensing progenitors in the developing cortex
Anna Alikhanbeigi (Utrecht)
P2.2 ER cisternae-microtubule interactions regulate dendrite development
Semanti Das (Utrecht)
P2.3 The effect of in utero exposure to THC on the development of midbrain dopaminergic neurons
Susanne Hazenberg (Amsterdam)
P2.4 Autonomic innervation on a chip: from brainstem to cardiac muscle
Marthe Kaal (Enschede)
P2.5 Functional connectivity changes during the menopausal transition
Bernardo Maciel (Amsterdam)
P2.6 Mind the VAP: how endoplasmic reticulum contact sites regulates axonal mRNA localization
Adriana Poza Rodríguez (Utrecht)
P2.7 Marked by early life stress: increased levels of MMP8+ cells in the hippocampus
Martin van der Jagt (Utrecht)
P2.8 Lipid raft restricted second messenger signalling and membrane trafficking in Ephrin-A5–mediated axon guidance
Ethan Wickens (Amsterdam)
P2.9 Elucidating the protein interactome at ER-organelle contact sites
Meizhen Xie (Utrecht)
P2.10 From body parts to behaviour: automated tracking of dams exposed to early life stress
Martijn Zegelaar (Utrecht)
P2.11 Localisation of a protein complex regulating fluid homeostasis in astrocyte endfeet in models for megalencephalic leukoencephalopathy with subcortical cysts
Felix Blokbergen (Amsterdam)
P2.12 Region and age-related microglia heterogeneity in the healty human frontal cortex
Pietro Colombo (Amsterdam)
P2.13 ER cisternae and tubules cooperatively support dendritic spine growth during synaptic activity
Koen Couperus (Amsterdam)
P2.14 Resolving how interactions between the post-synaptic density and the actin cytoskeleton drive activity-dependent reorganization of the synapse at the nanoscale
Diaz Danko (Amsterdam)
P2.15 The glial side of stress: investigating astrocyte and microglial dynamics in trauma susceptibility
Sandra de Mooij (Nijmegen)
P2.16 Activity-driven axonal plasticity in parvalbumin interneurons
Blaire Japhet Domingo (Amsterdam)
P2.17 Functional impact of GluN2B-NMDAR LoF variants on developing neural networks in vitro
Sophie Lee (Amsterdam)
P2.18 The effect of norepinephrine on cAMP-PKA signaling in inhibitory hippocampal interneurons
Bart Lelie (Nijmegen)
P2.19 Ictal phase–amplitude coupling tracks hippocampal epileptogenesis
Zhongyi Li (Rotterdam)
P2.20 Characterizing microglia morphology 3 hours after LPS stimulation
Fee Offerman (Amsterdam)
P2.21 Dopaminergic stimulation drives inhibitory bouton formation via PKA activity
Cathal Rollins (Nijmegen)
P2.22 Characterisation of dendritic and axonal arborisation of the cortical chandelier cell
Johanna Seemann (Amsterdam)
P2.23 Resolving the nanoscale organization of AMPA receptor auxiliary subunits in the synapse
Lieke Steijvers (Amsterdam)
P2.24 Investigating the emergence of functional neuronal networks in the absence of developmental activity
Lena Teunissen (Nijmegen)
P2.25 Sex-dependent effects of testosterone on intrinsic and network properties of excitatory CA1 hippocampal neurons
Tessa Tuinzaad (Nijmegen)
P2.26 Development of a rapid and reversible degradation system for synaptic actin-regulating proteins
Ruben van Amerom (Amsterdam)
P2.27 Towards an in vitro model to study mechanisms of astrocyte-synapse interactions
Marleen van den Munkhof (Amsterdam)
P2.28 Energetic constraints of human L2/3 pyramidal neurons during sustained high-frequency activity
Imme van der Knaap (Amsterdam)
P2.29 Understanding the molecular mechanisms underlying astrocyte endfeet dynamics
Eva van der Meer (Amsterdam)
P2.30 The effect of Gi- and Gq-protein coupled receptor activation on inhibitory bouton dynamics in the mouse hippocampal CA1 region
Floor van Heijnsbergen (Nijmegen)
P2.31 Molecular and functional identification of CD200-CD200R interactions in neuron-glia signaling
David van Lee (Amsterdam)
P2.32 Cellular mechanisms setting local rules of spike-timing dependent plasticity
Robin Weiler (Amsterdam)
P2.33 The AIS at the nanoscale: linking cytoskeleton remodelling to re-distribution of voltage-gated ion channels during acute AIS plasticity
Noémie Zerrouki (Amsterdam)
P2.34 Dissecting the role of skeletal muscle in TDP-43-associated ALS
Maja Anuszewska (Nijmegen)
P2.35 Study of the mitochondrial malate-aspartate shuttle in Dars1 and Dars2 mouse model of leukoencephalopathies
Olivia Belt (Amsterdam)
P2.36 Investigation of neurons in the suprachiasmatic nucleus in postmortem brain of people with type 1 Diabetes Mellitus
Tara Brinker (Amsterdam)
P2.37 Investigating molecular pathways involved in hippocampal synaptic potentiation using advanced optic tools
Andrea Caldarola (Amsterdam)
P2.38 Effects of early-handling and sex on cognitive resilience in APP/PS1 mice
Maria Carrigan (Amsterdam)
P2.39 The effect of γ-secretase activity on lipid metabolism in ESC/iPSC-derived oligodendrocytes
Antonia Coman (Amsterdam)
P2.40 Are SARS_CoV-2 and Parkinson's disease connected?
Anouk Dijkstra (Rijswijk)
P2.41 The transcriptomic landscape of xenografted human microglia and their cellular interactions in Alzheimer’s disease
Beáta Gaálová (Groningen)
P2.42 Extracellular vesicles mediate a neuroprotective effect in PINK1 knockout neural progenitor cells under mitochondrial-induced stress
Saskia Gooijer (Groningen)
P2.43 Effects of an early-life ω-3 PUFA dietary intervention on lipidomic profiling in cortex and hippocampus of APP/PS1 and wild-type mice
George Hogenboom (Amsterdam)
P2.44 Predicting Alzheimer’s disease from human EEG signals
Sara Juganaru (Groningen)
P2.45 Supporting the oligodendrocyte-neuron coupling: pulling back the curtain on downstream PDE4D signalling
Freddy Leenders (Maastricht)
P2.46 A phage-based platform for the detection and targeting of amyloid-β oligomers in Alzheimer’s Disease
Alexandre Lima (Amsterdam)
P2.47 Microglial GABAB signaling links parvalbumin interneuron hyperactivity to synaptic pathology in AppNL-G-F alzheimer mice
Teun Meere (Amsterdam)
P2.48 Effects of early handling and sex on Alzheimer’s disease pathology in 12-month-old APP/PS1 mice
Olga Minko (Amsterdam)
P2.49 Early-life dietary enrichment with n-3 PUFAs shows no detectable effect on amyloid pathology in female APP/PS1 mice at 6 months of age
Joanna Ñañez (Amsterdam)
P2.50 Analysis of the mitochondrial electron transport chain in the central nervous system of Dars2 mutant mice
Sara Nulli (Amsterdam)
P2.51 Development of an AAV-mediated α-synuclein non-human primate model of Parkinson’s disease
Erik Nutma (Rijswijk)
P2.52 Unravelling how loss of fumarase 1 function triggers adult-onset neurodegeneration
Müjgan Özcan (Nijmegen)
P2.53 Isolating GFP+ neural stem cells from the neurogenic niches of mesenchymal stem cell-treated hypoxic-ischemic mice
Suzanne Paauw (Utrecht)
P2.54 Longitudinal multilevel EEG markers of dynamic network reorganization after mild traumatic brain injury: evidence from neural criticality and delta-band connectivity
Sofie Paludanus (Den Haag)
P2.55 Tau aggregation causes selective dendrite loss in iPSC-derived human neurons
Robin Pelle (Amsterdam)
P2.56 APOE4-driven astrocyte senescence as a contributor to Alzheimer’s disease pathology
Jennet Pirkuliyeva (Amsterdam)
P2.57 EEG-based biomarkers of anti-seizure medication efficacy in patients with refractory focal epilepsy
Zoë Thépass (Leiden)
P2.58 AAV-mediated elevation of glycyl-tRNA levels reverses peripheral neuropathy in mouse models of GARS1-associated Charcot-Marie-Tooth disease
Kes van Blitterswijk (Nijmegen)
P2.59 Consequences of artificial light at night on hippocampal memory in 3xTg-AD male and female mice
Rianne van Dekken (Groningen)
P2.60 Deep brain stimulation mechanisms in Parkinson’s disease via voltage imaging
Maxime van Veghel (Rotterdam)
P2.61 Cholinergic neurons in the nucleus basalis of meynert in prader-willi syndrome
Anne Sophie Versteegh (Amsterdam)
P2.62 Oxidative stress induces the integrated stress response in human astrocytes
Saloua Zekri (Amsterdam)
P2.63 PINK1 modulates diesel exhaust particle-induced dysfunction in human iPSC-derived microglia
Leshan Zhang (Groningen)
P2.64 The effect of PTPA variants on neuronal function and α-synuclein phosphorylation in Parkinson’s disease
Irina Zogina (Rotterdam)
P2.65 M13 bacteriophage to quantify changes in amyloid-β oligomer load following an immune challenge in APP/PS1 mice
Verena Zwetsloot (Amsterdam)
P2.66 Establishing hiPSC-derived 2D and 3D neuron-astrocyte models to study CACNA1A-related neuronal network activity
Neslihan Akbulut (Nijmegen)
P2.67 Physiological alterations underlying attack susceptibility in the D801N AHC mouse model
Zoë Bor (Leiden)
P2.68 Whole-brain cellular mapping of sex-specific system-level organization in autism spectrum disorder
Jeske Enzerink (Nijmegen)
P2.69 Understanding soma-restricted distribution of CAMK2G variants associated with neurodevelopmental disorders
Maike Hinrichs (Rotterdam)
P2.70 Markerless pose estimation and post-tracking behavioral phenotyping to assess the effect of early life stress and adult complex housing on stress response and social behavior in mice
Yasin Karyagdi (Amsterdam)
P2.71 Pathogenic variants in GPRC5B drive chronic brain oedema in MLC and identify GPRC5B as a therapeutic target
Freya Kirwan (Amsterdam)
P2.72 Looking at neurodevelopmental disorders through the lens of evolution: a role for the autolysosomal pathway
Elly Lewerissa (Nijmegen)
P2.73 Temporal processing in ADHD, autism, and their co-occurrence: a comparison with typically developing children
Alina Munteanu (Rotterdam)
P2.74 An iPSC-derived organoid model of hypoxic-ischemic brain injury to test extracellular vesicle treatment
Stela Papadaki (Utrecht)
P2.75 Sleep-related neuronal network impairments associated with paroxysmal attacks in a mouse model of Alternating Hemiplegia of Childhood
Chiara Rasconà (Leiden)
P2.76 Decoding the RNF12 neural interactome: a FLAG IP-MS proteomics pipeline to identify TOKAS syndrome substrates
Maurits Unkel (Rotterdam)
P2.77 The effect of sleep quality on PPI, startle response and habituation in adults with autism compared to neurotypical adults
Lois van der Wijck (Den Haag)
P2.78 The effects of Tcf4 haploinsufficiency on play, sociability and communication in mice
Francis van Rookhuizen (Amsterdam)
P2.79 The effect of CHD2 haploinsufficiency on the autolysosomal function in hiPSC-derived astrocytes
Patrycja Wypych (Nijmegen)
P2.80 The effects of oral tributyrine supplementation in a double-hit depression model in mice
Bibi Bek (Amsterdam)
P2.81 The impact of maternal depression and antidepressant treatment on the maternal immune system
Luna Does (Amsterdam)
P2.82 The development of the Aggression Neuropsychological Assessment battery
Zain Gangaram (Maastricht)
P2.83 Escaping harm or earning reward: avoidance behavior in Sapap3-KO mice in an active avoidance task
Aikaterini Moysiadou (Amsterdam)
P2.84 Impact of prenatal stress on the maternal (neuro)immune system
Meike Mulder (Amsterdam)
P2.85 A multi-angle approach to study synaptic E/I coordination in major depressive disorder
Bas Ooijman (Nijmegen)
P2.86 Does butyrate have therapeutic potential for treating depression? A preclinical intervention study
Luca Rietveld (Amsterdam)
P2.87 The role of the endocannabinoid system in stress-induced depression
Lisette Siebert-ten Bolscher (Amsterdam)
P2.88 Early-life stress in future mothers: hippocampal microglia during pregnancy
Ines Vroegop (Amsterdam)
P2.89 Establishing in vivo fiber photometry to investigate developmental aspects of elevated serotonin levels in somatosensory signal processing
Nur Bodur (Nijmegen)
P2.90 Mapping functional and anatomical organizations of somatosensory projections in the lateral cortex of the inferior colliculus
Elena Compas (Rotterdam)
P2.91 Dissecting the relationships between biophysical, morphological and
electrophysiological properties of cortical dendrites
Su Saka (Amsterdam)
P2.92 Contribution of the primary visual cortex to compensatory eye movements function and development
Lisa-Maria Galca (Rotterdam)
P2.93 Optogenetic manipulation of dorsolateral striatum medium spiny neuronal subpopulations during locomotion
Meike Jongen (Amsterdam)
P2.94 High-speed GEVI fiber photometry in mice to investigate mechanisms of deep brain stimulation in Parkinson’s disease
Denis Torbin (Rotterdam)
P2.95 Wave-like striatal dopamine peaks and troughs bracket spontaneous movement
Nynke van Walraven (Amsterdam)
P2.96 Investigating neurotoxicity in C. elegans during ageing: The role of quinolinic acid in mediating the protective effect of TDO-2 depletion
Jules Borgers (Groningen)
P2.97 Attractiveness of zebra finches songs: Calcium imaging and behavioral preference male song perception in a secondary auditory cortex-like brain region in female songbirds
Linda De Pellegrin (Groningen)
P2.98 Memory in motion: in vivo calcium imaging to investigate the neural substrate of tutor song memory in adult zebra finches
Hidde Huisjes (Groningen)
P2.99 Hepatic clocks and behavioural rhythmicity: is GPR146 the underlying factor driving food entrainment in mice?
Indy Lopers (Groningen)
P2.100 The hidden grammar of behaviour: a computational qpproach to reveal grooming microstructure
Elizaveta Tatarnikova (Amsterdam)
P2.101 Neural and behavioral mechanisms of approach–avoidance conflict
Rafaela Gamboa von Groll (Amsterdam)
P2.102 Hemispheric lateralization of DRD1-expressing medial amygdala projections in downstream pathways related to metabolic regulation
Anastasia Marin (Amsterdam)
P2.103 Early-life stress and later environmental modulations: impact on cortical plasticity and optimizing THC-vapor exposure in mice
Roos van der Laan (Amsterdam)
P2.104 Cocaine-induced conditioned place preference in serotonin transporter knockout rats is reduced by monoaminergic vesicle depletion
Emanuela Vescan & Iwan van Oosterhout (Nijmegen)
P2.105 What are we? Diving into how pairbonding shapes female zebra finch perception
Andrés Viñas Martínez (Groningen)
P2.106 GluA3-dependent regulation of parvalbumin-expressing interneurons and hippocampal memory dysfunction in Alzheimer’s disease
Alisha Balhari (Amsterdam)
P2.107 Linking representational drift to plasticity in biologically inspired continual learning
Nikola Bátová (Groningen)
P2.108 Optimizing activity-dependent labeling for locus coeruleus stress ensembles: a comparative study
Weronika Gnat (Amsterdam)
P2.109 A semi-naturalistic approach to charting rodent neuro-cognitive development and their interaction with the early life environment
José Gomes Teixeira (Nijmegen)
P2.110 Combining real and simulated neurons to evaluate predictive hippocampal representations
Paula Gómez Méndez (Groningen)
P2.111 The impact of ecologically relevant stimuli in assessing basic cognitive functions in rhesus macaques: implications for translational models
Katarina Koch (Rijswijk)
P2.112 Discriminating sex chromosome and gonadal hormone influences on hippocampal pattern separation with a touchscreen-based task
Saga Lehtimäki (Groningen)
P2.113 Structural brain effects of estrogen depletion in a mouse model of Alzheimer’s disease: a longitudinal deformation-based morphometry study
Jacek Menżyński-Biskup (Groningen)
P2.114 Structural changes following ovarian removal combined with circadian disturbances in a mouse model of AD
Thijs Peters (Groningen)
P2.115 Stochastic exploration of cortical microcircuit models for predictive processing
Max Rensen (Nijmegen)
P2.116 The impact of adolescent risk exposure on cognitive control and inhibition in Lister Hooded rats
Linde van Dijken (Utrecht)
P2.117 The role of theta oscillations in memory retrieval
Livia Stein (Groningen)
P2.118 Unmasking cell type-specific epigenetics through low-input nanopore sequencing
Lisa Koole (Maastricht)
P2.119 Optimising doxycycline treatment duration for maturation of rapidly induced iPSC-derived neurons
Dimah Shaban (Amsterdam)
P2.120 Computer vision-based framework for quantitative assessment of facial motor and speech function in awake brain surgery
Cindy Steward (Rotterdam)
P2.121 Using (high-density) micro-electrode array recordings to assess acute and developmental neurotoxicity in human iPSC-derived neuronal cultures after exposure to environmental contaminants
Lennart van Melis (Utrecht)
P2.122 The role of juvenile risky play in shaping decision-making in adult Lister Hooded rats
Michelle Smolenaers (Utrecht)
The two poster sessions are scheduled for Thursday, 25 June, at 17:15 and Friday, 26 June, at 16:45.
If your abstract is selected for a poster presentation, when preparing your poster please remember that the maximum area available is 96 x 122 cm (width x height); the poster must have a portrait format. We recommend preparing your poster in a standard A0 size (841 x 1189 mm; width x height).
"Portrait" is fine
"Landscape" not...
Your poster should be readable from a 2-metre distance; as a rough guideline, use a font size of 72 pts for your title, and a minimum of 28 pts for your text.
Posters must be mounted on the day of the presentation only, between 08:00 and the start of the first session of the day (10:00 on Thursday, and 09:00 on Friday).
Posters must be removed at the end of the day only: 18:30 on Thursday and Friday. Posters from the Thursday session that are still up by Friday at 08:00 will be discarded by the venue personnel so that the Friday posters can be set up. Posters left behind after the conclusion of the meeting will be discarded by the venue personnel.